Vaccine aluminum adjuvant causation of neuroglial activation and neuroinflammation in the brain of patients with autism- Page 2
This is enough information and from Suzanne Humphries should be in itself enough to shut down the entire CDC directed infant vaccination schedule. But you know that again they will ignore it; and because not to would obviously finish them entirely.
Suzanne Humphries, MD - Neonatal Immunity: The first 3 years of life: (the above video)
“Nothing should interfere with the immunologic programming, especially during the first three years.” Normal brain development depends on the baby maintaining a non-inflammatory state. Vaccines drive excessive inflammation and can derail normal brain development:
https://www.youtube.com/watch?v=wL8srdLw4c0
Dr. Suzanne Humphries Has A Lot To Say About Aluminum In Vaccines
“By the age of 18 months, that infant has already received 4,925 micrograms (mcg) of aluminum, 100 percent of which is absorbed since it’s given intramuscularly. In the 1980s the amount of aluminum you got when following the childhood vaccination schedule amounted to 1,120 mcg, and importantly, it was given in more mature babies, not newborns. Today, American children end up getting a grand total of 6,150 mcg of aluminum if they get all of their recommended vaccines.”
Read more:
http://www.collective-evolution.com/2015/04/20/dr-suzanne-humphries-has-a-lot-to-say-about-aluminum-in-vaccines/
Dr Suzanne Humphries. Aluminum is toxic to all life forms: The case against aluminum in vaccines. (the above video)
https://youtu.be/LZe99K12740
Vaccination: The Neurological Poison So Common Your Doctor Probably Pushes It
http://articles.mercola.com/sites/articles/archive/2012/04/11/vaccination-impact-on-childrens-health.aspx
Dr. Paul Offit’s Aluminum Deceptions and Academic Misconduct (one very important article, to read)
http://vaccinepapers.org/dr-paul-offits-aluminum-deceptions-academic-misconduct/
The Defense of Aluminum Adjuvant, Debunked
http://vaccinepapers.org/rigorous-defense-al-adjuvant-wrong/
Part 1: Immune Activation and Autism
http://vaccinepapers.org/rigorous-defense-al-adjuvant-wrong/
See all posts on Immune Activation
Part 1: Immune Activation and Autism
Part 2: Interleukin-6 and Autism
Part 3: Monkey Experiments
Part 4: (Coming Soon) Prenatal vs. Postnatal Immune Activation
http://vaccinepapers.org/immune-activation/
Scientific Papers Library
Immune Activation
http://vaccinepapers.org/scientific-papers-library/
A More Rigorous Defense of Al Adjuvant, and Why it is Wrong
http://vaccinepapers.org/rigorous-defense-al-adjuvant-wrong/
VRM: The Problem With Vaccines Part 2 – Synergistic Effect of Heavy Metal Toxicity On The Body
http://vaccineresistancemovement.org/?p=6097
The Mechanisms of Vaccine Injury and Via Cytokine Storm
http://www.vacfacts.info/the-mechanisms-of-vaccine-injury-and-via-cytokine-storm.html
Vaccination toxicity: The Zeta phase of MASS and “blood sludging”
http://www.vacfacts.info/vaccination-toxicity-the-zeta-phase-of-mass-and-ldquoblood-sludgingrdquo.html
Unvaccinated Children Will Be Healthiest Among Future Generations Studies and Surveys Predict
http://www.fhfn.org/unvaccinated-children-will-be-healthiest-among-future-generations-studies-and-surveys-predict/
Journal of Toxicology- Aluminum
Volume 2009 (2009), Article ID 532640,
http://dx.doi.org/10.1155/2009/532640
Published Research
Aluminum Vacciune Adjuvants
Mercury - Neurological and Immune Development
http://www.cmsri.org/published-research/
J Expo Sci Environ Epidemiol. 2010 Nov;20(7):598-601. doi: 10.1038/jes.2009.64. Epub 2009 Dec 16.
Infants' exposure to aluminum from vaccines and breast milk during the first 6 months.
Dórea JG1, Marques RC.
Abstract
The success of vaccination programs in reducing and eliminating infectious diseases has contributed to an ever-increasing number of vaccines given at earlier ages (newborns and infants). Exposure to low levels of environmental toxic substances (including metals) at an early age raises plausible concerns over increasingly lower neuro-cognitive rates. Current immunization schedules with vaccines containing aluminum (as adjuvant) are given to infants, but thimerosal (as preservative) is found mostly in vaccines used in non-industrialized countries. Exclusively, breastfed infants (in Brazil) receiving a full recommended schedule of immunizations showed an exceedingly high exposure of Al (225 to 1750 μg per dose) when compared with estimated levels absorbed from breast milk (2.0 μg). This study does not dispute the safety of vaccines but reinforces the need to study long-term effects of early exposure to neuro-toxic substances on the developing brain. Pragmatic vaccine safety needs to embrace conventional toxicology, addressing especial characteristics of unborn fetuses, neonates and infants exposed to low levels of aluminum, and ethylmercury traditionally considered innocuous to the central nervous system.
http://www.ncbi.nlm.nih.gov/pubmed/20010978
Tox-Guide For Aluminum-Al
http://www.atsdr.cdc.gov/toxguides/toxguide-22.pdf
Int J Alzheimers Dis. 2011 Mar 8;2011:276393. doi: 10.4061/2011/276393.
Link between Aluminum and the Pathogenesis of Alzheimer's Disease: The Integration of the Aluminum and Amyloid Cascade Hypotheses.
Kawahara M1, Kato-Negishi M.
Abstract
Whilst being environmentally abundant, aluminum is not essential for life. On the contrary, aluminum is a widely recognized neurotoxin that inhibits more than 200 biologically important functions and causes various adverse effects in plants, animals, and humans. The relationship between aluminum exposure and neurodegenerative diseases, including dialysis encephalopathy, amyotrophic lateral sclerosis and Parkinsonism dementia in the Kii Peninsula and Guam, and Alzheimer's disease (AD) has been suggested. In particular, the link between aluminum and Alzheimer's disease has been the subject of scientific debate for several decades. However, the complex characteristics of aluminum bioavailability make it difficult to evaluate its toxicity and therefore, the relationship remains to be established. Mounting evidence has suggested that significance of oligomerization of β-amyloid protein and neurotoxicity in the molecular mechanism of AD pathogenesis. Aluminum may play crucial roles as a cross-linker in β-amyloid oligomerization. Here, we review the detailed characteristics of aluminum neurotoxicity based on our own studies and the recent literatures. Our aim is to revisit the link between aluminum and AD and to integrate aluminum and amyloid cascade hypotheses in the context of β-amyloid oligomerization and the interactions with other metals.
http://www.ncbi.nlm.nih.gov/pubmed/21423554
Review Article
Aluminum-Induced Entropy in Biological Systems:
Implications for Neurological Disease
5. Conclusions
Aluminuminducesentropyinlivingorganismsbydisrupting
all levels of structure from water molecules through all
biosemiotic systems. Entropy-inducing cascades, feedback
loops (positive and negative) within and across levels, can
damage DNAs, RNAs, proteins, cells, tissues, and whole organ
systems. As a result of cellular damage caused by an
Al compound, injured and dying cells will release proteases,
excitatory amino acids, and ions (e.g., potassium, calcium),
disrupting biosemiosis at many levels. Toxic effects of Al and
its compounds thus tend to proliferate. Interactive results
involving immune functions, for instance, make the impact
worse than if only one system were involved. Of course, the
dose-response of Al and its compounds must be considered,
but even at low doses, especially with repeated exposures, Al
can have cumulative deleterious effects that can be extreme
and even fatal. For that reason, a repeated low dose exposure
may prove more damaging than a single larger dose. Al
and its compounds can cross biosemiotic levels, damaging
genetic systems, proteins, cells, and all systems up through
the CNS. While higher doses may rapidly affect multiple
levels, as in dialysis-associated encephalopathy (DAE), low
doses over time, for example, from vaccines, can degrade
metabolism and disrupt repair and defense systems and can
spiraloutofcontrolasinASIA.Aladjuvantsinvaccinesmay
hyperdrive the immune functions of the body but they also
directly disrupt biosemiotic systems. Sound theory, empirical
research, and reasonable inferences from sources cited here
show that Al and its compounds damage biological systems.
Such conclusions warrant considerations at a policy level to
limit human exposure to Al and its compounds
Read more:
http://people.csail.mit.edu/seneff/Shaw_et_al_JOT_2014.pdf
Treatment Manual for HPV Vaccine Injured
http://vaccineimpact.com/2015/treatment-manual-for-hpv-vaccine-injured/
Mass Vaccine Brainwashing Campaign Exposed
https://www.youtube.com/watch?feature=player_detailpage&v=S9HwpHDHFWo&app=desktop
How To Recognize the Signs And Symptoms of Vaccine Reactions
http://www.nvic.org/Downloads/4507NVIC11x17HIRES.aspx
Is Aluminum The New Thimerosal?
http://sarahjmuma.files.wordpress.com/2012/05/aluminum-new-thimerosal-sears.pdf
Research Article
The Severity of Autism Is Associated with Toxic Metal Body Burden and Red Blood Cell Glutathione Levels
Abstract
This study investigated the relationship of children's autism symptoms with their toxic metal body burden and red blood cell (RBC) glutathione levels. In children ages 3–8 years, the severity of autism was assessed using four tools: ADOS, PDD-BI, ATEC, and SAS. Toxic metal body burden was assessed by measuring urinary excretion of toxic metals, both before and after oral dimercaptosuccinic acid (DMSA). Multiple positive correlations were found between the severity of autism and the urinary excretion of toxic metals. Variations in the severity of autism measurements could be explained, in part, by regression analyses of urinary excretion of toxic metals before and after DMSA and the level of RBC glutathione (adjusted of 0.22–0.45, in all cases). This study demonstrates a significant positive association between the severity of autism and the relative body burden of toxic metals.
http://www.hindawi.com/journals/jt/2009/532640/ (full study)
Aluminum Induced Immunoexcitotoxicity in Neurodevelopmental and Neurodegenerative Disorders
Russell L. Blaylock*
Visiting Professor Biology Belhaven University Theoretical Neurosciences Research, LLC Ridgeland, Mississippi, USA
Abstract
A great deal has been learned about the neurotoxicity of aluminum over the past two decades in terms of its ability to disrupt cellular function. Newer evidence suggests that a more central pathophysiological mechanism may be responsible for much of the toxicity of aluminum and aluminofluoride compounds on the brain. This mechanism involves activation of the brainâ € ™ s innate immune system, primarily the microglia, with a release of neurotoxic concentrations of excitotoxins and pro-inflammatory cytokines, chemokines and immune mediators. A large number of studies suggest that excitotoxicity plays a significant role in the neurotoxic action of a number of metals, including aluminum. Recently, researchers have found that while most of the chronic neurodegenerative effects of these metals are secondary to prolonged inflammation, it is the enhancement of excitotoxicity by the immune mediators that is responsible for most of the metalâ € ™ s toxicity. This enhancement occurs via a crosstalk between cytokine receptors and glutamate receptors. The author coined the name immunoexcitotoxicity to describe this process. This paper reviews the evidence linking immunoexcitotoxicity to aluminums neurotoxic effects.
http://www.geoengineeringwatch.org/documents/Aluminum-Blaylock.pdf
Aluminum Induced Immunoexcitotoxicity in Neurodevelopmental and Neurodegenerative Disorders
http://chiropractorwestpalmbeach.net/2013/06/27/aluminum-induced-immunoexcitotoxicity-in-neurodevelopmental-and-neurodegenerative-disorders/
Raising A Vaccine Free Child, by Wendy Lydall
http://www.vaccinefreechild.com/
Fight Autism and Win! By parents for parents! (the Andy Cutler chelation protocol)
http://www.fightautismandwin.com/#sthash.XITmXJsq.dpbs
http://www.amazon.com/Fight-Autism-Win-Biomedical-Therapies/dp/0615582095
Autism, ADD, ADHD: 2014
“What’s Really Working?”
Featuring Amy Derksen, ND
With bonus lecture by Dietrich Klinghardt, MD. PHD
http://www.klinghardtacademy.com/images/stories/event/autism_add_adhd_whats_working_today.pdf
J Inorg Biochem. 2013 No;128:237-44. doi: 10.1016/j.jinorgbio.2013.07.022. Epub 2013 Jul 19.
Administration of aluminium to neonatal mice in vaccine-relevant amounts is associated with adverse long term neurological outcomes.
Shaw CA1, Li Y, Tomljenovic L.
Abstract
Our previous ecological studies of autism spectrum disorder (ASD) has demonstrated a correlation between increasing ASD rates and aluminium (Al) adjuvants in common use in paediatric vaccines in several Western countries. The correlation between ASD rate and Al adjuvant amounts appears to be dose-dependent and satisfies 8 of 9 Hill criteria for causality. We have now sought to provide an animal model to explore potential behavioural phenotypes and central nervous system (CNS) alterations using s.c. injections of Al hydroxide in early postnatal CD-1 mice of both sexes. Injections of a "high" and "low" Al adjuvant levels were designed to correlate to either the U.S. or Scandinavian paediatric vaccine schedules vs. control saline-injected mice. Both male and female mice in the "high Al" group showed significant weight gains following treatment up to sacrifice at 6 months of age. Male mice in the "high Al" group showed significant changes in light-dark box tests and in various measures of behaviour in an open field. Female mice showed significant changes in the light-dark box at both doses, but no significant changes in open field behaviours. These current data implicate Al injected in early postnatal life in some CNS alterations that may be relevant for a better understanding of the aetiology of ASD.
© 2013.
http://www.ncbi.nlm.nih.gov/pubmed/23932735
Exposure to Mercury and Aluminum in Early Life: Developmental Vulnerability as a Modifying Factor in Neurologic and Immunologic Effects
Abstract: Currently, ethylmercury (EtHg) and adjuvant-Al are the dominating interventional exposures encountered by fetuses, newborns, and infants due to immunization with Thimerosal-containing vaccines (TCVs). Despite their long use as active agents of medicines and fungicides, the safety levels of these substances have never been determined, either for animals or for adult humans—much less for fetuses, newborns, infants, and children. I reviewed the literature for papers reporting on outcomes associated with (a) multiple exposures and metabolism of EtHg and Al during early life; (b) physiological and metabolic characteristics of newborns, neonates, and infants relevant to xenobiotic exposure and effects; (c) neurobehavioral, immunological, and inflammatory reactions to Thimerosal and Al-adjuvants resulting from TCV exposure in infancy. Immunological and neurobehavioral effects of Thimerosal-EtHg and Al-adjuvants are not extraordinary; rather, these effects are easily detected in high and low income countries, with co-exposure to methylmercury (MeHg) or other neurotoxicants. Rigorous and replicable studies (in different animal species) have shown evidence of EtHg and Al toxicities. More research attention has been given to EtHg and findings have showed a solid link with neurotoxic effects in humans; however, the potential synergic effect of both toxic agents has not been properly studied. Therefore, early life exposure to both EtHg and Al deserves due consideration.
http://www.mdpi.com/1660-4601/12/2/1295/htm
Journal of American Nutraceutical Association 6: 21-35, 2003.
Interaction of Cytokines, Excitotoxins, and Reactive Nitrogen and Oxygen Species in Autism Spectrum Disorders, Russell Blaylock, MD* Medical Director, Advanced Nutritional Concepts Ridgeland, Mississippi
ABSTRACT
There is growing and compelling evidence that excessive peripheral as well as central immune activation of brain microglia can result in alterations in brain growth and connectivity during rapid brain growth, the so-called "brain growth spurt." A considerable amount of evidence, presented in this paper, demonstrates the deleterious effects of immune factors, such as cytokines, chemokines, and excitotoxins, when present in excess. The interaction between excitotoxicity, ROS and RNS injury and immune dysfunction is discussed. It is concluded that excessive activation of the brain's immune system during critical growth periods can occur when vaccines are given as combination vaccines, using schedules that are too close together or by the use of certain live viruses in the vaccines.
http://www.nutrimedical.com/news.jhtml?method=view&news.id=1084
Recent Changes In Vaccines
"They’ve been increasing the amount of aluminum in vaccines quite systematically particularly over the last 10 years,” says Dr. Stephanie Seneff, senior scientist at MIT who has been conducting research for over three decades. She is considered the leading expert on sulfur and how it functions in the body. She is an electrical engineer, a computer science specialist who then converted into the biological sciences with a biology degree as well as a food and nutrition specialty.
“They’ve been increasing the number of vaccines as well. I’m deeply disturbed by what I’m seeing,” she says. The root of her worry is, “They add the aluminum in order to get the child to react enough. If the child has a strong immune system and you just give them a vaccine of some dead microbe, the body’s going to slough it off – they won’t actually be resistant to the disease. They have to put something else in the vaccine to make you react more. They’ve discovered that aluminum works really well.” At the same time it’s causing all the trouble.
Read more:
http://nourishingplot.com/2014/06/27/recent-changes-in-vaccines/
The Mechanisms of Vaccine Injury and Via Cytokine Storm
http://www.vacfacts.info/the-mechanisms-of-vaccine-injury-and-via-cytokine-storm.html
Although this next study does not involve vaccines; if you follow the studies on these pages, you will realize how similar the same type of vaccine injury is, to traumatic brain injury; and it clearly involves the same or similar physiological and biological systems.
Surg Neurol Int. 2011; 2: 107.
Published online 2011 July 30. doi: 10.4103/2152-7806.83391
PMCID: PMC3157093
Immunoexcitotoxicity as a central mechanism in chronic traumatic encephalopathy—A unifying hypothesis
Published online 2011 July 30. doi: 10.4103/2152-7806.83391
PMCID: PMC3157093
Russell L. Blaylock* and Joseph Maroon1
Abstract
Some individuals suffering from mild traumatic brain injuries, especially repetitive mild concussions, are thought to develop a slowly progressive encephalopathy characterized by a number of the neuropathological elements shared with various neurodegenerative diseases. A central pathological mechanism explaining the development of progressive neurodegeneration in this subset of individuals has not been elucidated. Yet, a large number of studies indicate that a process called immunoexcitotoxicity may be playing a central role in many neurodegenerative diseases including chronic traumatic encephalopathy (CTE). The term immunoexcitotoxicity was first coined by the lead author to explain the evolving pathological and neurodevelopmental changes in autism and the Gulf War Syndrome, but it can be applied to a number of neurodegenerative disorders. The interaction between immune receptors within the central nervous system (CNS) and excitatory glutamate receptors trigger a series of events, such as extensive reactive oxygen species/reactive nitrogen species generation, accumulation of lipid peroxidation products, and prostaglandin activation, which then leads to dendritic retraction, synaptic injury, damage to microtubules, and mitochondrial suppression. In this paper, we discuss the mechanism of immunoexcitotoxicity and its link to each of the pathophysiological and neurochemical events previously described with CTE, with special emphasis on the observed accumulation of hyperphosphorylated tau.
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3157093/
Download PDF: Immunoexcitotoxicity as a central mechanism in chronic traumatic encephalopathy-A unifying hypothesis
http://www.surgicalneurologyint.com/downloadpdf.asp?issn=2152-7806%3Byear%3D2011%3Bvolume%3D2%3Bissue%3D1%3Bspage%3D107%3Bepage%3D107%3Baulast%3DBlaylock%3Btype%3D2
Session 22, The Vaccine Safety Conference: Dr. Russell Blaylock, MD, CCN
THE CENTRAL ROLE OF IMMUNOEXCITOTOXICITY IN ALUMINUM AND MERCURY-CONTAINING ADJUVANT-TRIGGERED NEURODEVELOPMENTAL AND NEURODEGENERATIVE DISORDERS
http://www.youtube.com/watch?v=u9DkcpEEBPI
Dr. Russell Blaylock, MD, CCN, video presentation -(same video as above, for an alternate source).
http://www.vaccinesafetyconference.com/videos.html#BlaylockVideo
How Vaccines Harm Child Brain Development - Dr Russell Blaylock MD
http://www.youtube.com/watch?v=7QBcMYqlaDs
Vaccination and brain inflammation
http://www.heartmdinstitute.com/prevention/immunity/vaccinations/167-vaccines-depression-neurodegeneration-after-age-50-years?showall=&
Danger of live virus vaccines
http://www.heartmdinstitute.com/prevention/immunity/vaccinations/167-vaccines-depression-neurodegeneration-after-age-50-years?showall=&
A Mechanism of Toxicity of Aluminium-based Adjuvants?
Consumer Summary | by Chris Exley
http://www.vaccinesafetyconference.com/exley
Exley & House (2011) Aluminium in the human brain. Monatsh Chem (In press)
http://www.springerlink.com/content/9550512205128414/
Aluminum as a Neurotoxin: The Evidence from Cell Culture, In Vivo, & Human Studies
http://www.vaccinesafetyconference.com/pdf/Shaw/Shaw_PPT.pdf
Study Reveals Children are Being Vaccinated With Toxic Levels of Aluminium Causing Neurological Damage & Autism
A recent study conducted by Canadian scientists Professor Christopher Shaw and Dr. Lucija Tomljenovic revealed that the more vaccines that children receive containing the adjuvant aluminum, the greater their chance is of developing autism, autoimmune diseases and neurological problems in the future.
In 2013, in their paper, published by Springer Science+Business Media, titled Aluminum in the Central Nervous System: Toxicity in Humans and Animals, Vaccine Adjuvants, and Autoimmunity, they revealed that during a 17-year period, the rates of autism had increased significantly in countries that had the most vaccinations containing the adjuvant aluminum.
A Highly Significant Correlation
The researchers compared the number of vaccines recommend by the Centers for Disease Control and Prevention (CDC) during the period from 1991 – 2008 and the changes in the autism rates during the same period. They wrote:
“The data sets, graphed against each other, show a pronounced and statistically highly significant correlation between the number vaccines with aluminum and the changes in autism rates. Further data showed that a significant correlation exists between the amounts of aluminum given to preschool children and the current rates of autism in seven Western countries. Those countries with the highest level of aluminum-adjuvanted vaccines had the highest autism rates.” [1] (own emphasis)
Read more:
http://www.thelibertybeacon.com/2014/06/23/study-reveals-children-are-being-vaccinated-with-toxic-levels-of-aluminium-causing-neurological-damage-autism/
Dr. Chris Shaw discusses the toxic side effects of Aluminum in Vaccines. Oct-21-2009, (very informative)
https://www.youtube.com/watch?v=LsAKoRx60xs
Review of Vaccine Induced Immune Overload and the Resulting Epidemics of
Type 1 Diabetes and Metabolic Syndrome, Emphasis on Explaining the Recent
Accelerations in the Risk of Prediabetes and other Immune Mediated Diseases
Abstract
There has been an epidemic of inflammatory diseases that has paralleled the epidemic on iatrogenic immune
stimulation with vaccines. Extensive evidence links vaccine induced immune over load with the epidemic of type 1
diabetes. More recent data indicates that obesity, type 2 diabetes and other components of metabolic syndrome are
highly associated with immunization and may be manifestations of the negative feedback loop of the immune system
reacting to the immune overload. The epidemic of diabetes/prediabetes appears to be accelerating at a time when
the prevalence of obesity has stabilized, indicating that the negative feedback system of the immune system has
been over whelmed. The theory of vaccine induced immune overload can explain the key observations that have
confounded many competing hypothesis. The current paper reviews the evidence that vaccine induced immune
overload explains the disconnect between the increase in prediabetes and nonalcoholic fatty liver at a time when the obesity epidemic is waning in children.
http://vaccines.net/vaccine-induced-immune-overload.pdf
Do aluminum vaccine adjuvants contribute to the rising prevalence of autism?
Lucija Tomljenovic a, Christopher A. Shaw a,b
http://pop.1796kotok.com/pdfs/Aluminum_autism.pdf
DR. CHRIS SHAW: ALUMINUM IN THE BODY - ONE MORE GIRL EXCERPTS
http://www.youtube.com/watch?v=FfTo35UrFPA
Abstract for talk: Aluminum as a neurotoxin: the evidence from cell culture, in vivo, and
human studies
http://www.vaccinesafetyconference.com/pdf/Shaw/Shaw_CS.pdf
Autism Spectrum Disorders and Aluminum Vaccine Adjuvants
Lucija Tomljenovic, Russell L. Blaylock, Christopher A. Shaw
Abstract
Impaired brain function, excessive inflammation, and autoimmune manifestations are common in autism. Aluminum (Al), the most commonly used vaccine adjuvant, is a demonstrated neurotoxin and a strong immune stimulator. Hence, adjuvant Al has the necessary properties to induce neuroimmune disorders. Because peripheral immune stimuli in the postnatal period can compromise brain development and cause permanent neurological impairments, the possibility that such outcomes could also occur with administration of Al vaccine adjuvants needs to be considered. In regard to the risk of adjuvant toxicity in children, the following should be noted: (i) children should not be viewed as “small adults” as their unique physiology makes them more vulnerable to toxic insults; (ii) in adult humans Al adjuvants can cause a variety of serious autoimmune and inflammatory conditions including those affecting the brain, yet children are routinely exposed to much higher amounts of Al from vaccines than adults; (iii) compelling evidence has underscored the tight connection between the development of the immune system and that of the brain. Thus, it appears plausible that disruptions of critical events in immune development may also play a role in the establishment of neurobehavioral disorders; (iv) the same immune system components that play key roles in brain development appear to be targeted for impairment by Al adjuvants. In summary, research data suggests that vaccines containing Al may be a contributing etiological factor in the increasing incidence of autism.
http://link.springer.com/referenceworkentry/10.1007%2F978-1-4614-4788-7_89
Alzheimers
Int J Alzheimers Dis. 2012;2012:914947. doi: 10.1155/2012/914947. Epub 2012 Jul 30.
Cognitive deterioration and associated pathology induced by chronic low-level aluminum ingestion in a translational rat model provides an explanation of Alzheimer's disease, tests for susceptibility and avenues for treatment.
Walton JR.
Abstract
A translational aging rat model for chronic aluminum (Al) neurotoxicity mimics human Al exposure by ingesting Al, throughout middle age and old age, in equivalent amounts to those ingested by Americans from their food, water, and Al additives. Most rats that consumed Al in an amount equivalent to the high end of the human total dietary Al range developed severe cognitive deterioration in old age. High-stage Al accumulation occurred in the entorhinal cortical cells of origin for the perforant pathway and hippocampal CA1 cells, resulting in microtubule depletion and dendritic dieback. Analogous pathological change in humans leads to destruction of the perforant pathway and Alzheimer's disease dementia. The hippocampus is thereby isolated from neocortical input and output normally mediated by the entorhinal cortex. Additional evidence is presented that Al is involved in the formation of neurofibrillary tangles, amyloid plaques, granulovacuolar degeneration, and other pathological changes of Alzheimer's disease (AD). The shared characteristics indicate that AD is a human form of chronic Al neurotoxicity. This translational animal model provides fresh strategies for the prevention, diagnosis, and treatment of AD.
http://www.ncbi.nlm.nih.gov/pubmed/22928148
NEW STUDY REVEALS CHILDREN BEING VACCINATED WITH TOXIC LEVELS OF ALUMINUM CAUSING NEUROLOGICAL DAMAGE AND AUTISM
In their landmark 2013 paper, Canadian scientists Professor Christopher Shaw and Dr. Lucija Tomljenovic show that the more children receive vaccines with aluminum adjuvants, the greater their chance is of developing autism, autoimmune diseases and neurological problems later in life. A demonstrated neurotoxin, Aluminum is the only approved adjuvant in the US. Its use presents the risk of brain inflammation, autoimmunity and other adverse health consequences.
http://www.fhfn.org/new-study-reveals-children-being-vaccinated-with-toxic-levels-of-aluminum-causing-neurological-damage-and-autism/
Immunol Res. 2013 Jul;56(2-3):304-16. doi: 10.1007/s12026-013-8403-1.
Aluminum in the central nervous system (CNS): toxicity in humans and animals, vaccine adjuvants, and autoimmunity.
http://www.ncbi.nlm.nih.gov/pubmed/23609067
Administration of aluminium to neonatal mice in vaccine-relevant amounts is associated with adverse long term neurological outcomes
C.A. Shawa,b,c, ⁎, Y. Li a , L. Tomljenovic a
Abstract:
Our previous ecological studies of autism spectrum disorder (ASD) has demonstrated a correlation between increasing ASD rates and aluminium (Al) adjuvants in common use in paediatric vaccines in several Western countries. The correlation between ASD rate and Al adjuvant amounts appears to be dose-dependent and satisfies 8 of 9 Hill criteria for causality. We have now sought to provide an animal model to explore potential behavioural phenotypes and central nervous system (CNS) alterations using s.c. injections of Al hydroxide in early postnatal CD-1 mice of both sexes. Injections of a “high” and “low”Al adjuvant levels were designed to correlate to either the U.S. or Scandinavian paediatric vaccine schedules vs. control saline-injected mice. Both male and female mice
in the “high Al” group showed significant weight gains following treatment up to sacrifice at 6 months of age. Male mice in the “high Al” group showed significant changes in light–dark box tests and in various measures of behaviour in an open field. Female mice showed significant changes in the light–dark box at both doses, but no significant changes in open field behaviours. These current data implicate Al injected in early postnatal life in some CNS alterations that may be relevant for a better understanding of the aetiology of ASD. © 2013 Elsevier Inc
http://myofasciite.fr/Contenu/Divers/201307_CAShaw_YLee_LTomljenovic.pdf
PRESENTATIONS
http://www.vaccinesafetyconference.com/presentation.html
Study RESOURCES - Dr Russell Blaylock
http://www.vaccinesafetyconference.com/resources.html
The Danger of Excessive Vaccination During Brain Development
The Case for a Link to Autism Spectrum Disorders
By Russell L. Blaylock, M.D.
http://articles.mercola.com/sites/articles/archive/2008/03/14/the-danger-of-excessive-vaccination-during-brain-development.aspx
Immune-Glutamatergic Dysfunction as a Central Mechanism of the Autism Spectrum Disorders
http://citeseerx.ist.psu.edu/viewdoc/download?doi=10.1.1.317.7642&rep=rep1&
http://www.utdallas.edu/~mxa049000/lessons/research/literature/Autism/new/Blaylock%20autism%20rev%20CMC%2009.pdf
Chronic Microglial Activation and Excitotoxicity Secondary to Excessive Immune Stimulation:
Possible Factors in Gulf War Syndrome and Autism
The Role of Excitotoxicity
Page 47. Damage to neuronal mechanisms is not limited to direct cytokine effects. The excitotoxicity initiated by microglial activation is even more important. In cases of HIV-1 dementia, it is known that brain quinolinic acid, an excitotoxin secreted by activated microglia, can increase more than 300-fold. In addition, glutamate is released in concentrations that are known to destroy neurons and/or synaptic connections.
Because glutamate can also activate microglia and enhance cytokine-induced neurodegeneration, a vicious cycle is created in which immune cytokines can stimulate release of glutamate, and glutamate in turn enhances cytokine production and release. Moreover, cytokines inhibit glutamate transporters, which play a critical role in removal of excess extracellular glutamate. Intimately linked to excitotoxicity is the generation of destructive free radicals, especially the reactive nitrogen species such as peroxynitrite and nitrosoperoxycarbonate. Much of the injury to dendrites, synapses and neurons, by both cytokines and excitotoxicity, is caused by free radicals.
The Role of Vaccines, page 49
Read more:
http://www.jpands.org/vol9no2/blaylock.pdf
Entropy 2012, 14(8), 1399-1442; doi:10.3390/e14081399
Review
The Initial Common Pathway of Inflammation, Disease, and Sudden Death
Robert M. Davidson 1,* and Stephanie Seneff
Abstract: In reviewing the literature pertaining to interfacial water, colloidal stability, and cell membrane function, we are led to propose that a cascade of events that begins with acute exogenous surfactant-induced interfacial water stress can explain the etiology of sudden death syndrome (SDS), as well as many other diseases associated with modern times. A systemic lowering of serum zeta potential mediated by exogenous cationic surfactant administration is the common underlying pathophysiology. The cascade leads to subsequent inflammation, serum sickness, thrombohemorrhagic phenomena, colloidal instability, and ultimately even death. We propose that a sufficient precondition for sudden death is lowered bioavailability of certain endogenous sterol sulfates, sulfated glycolipids, and sulfated glycosaminoglycans, which are essential in maintaining biological equipose, energy metabolism, membrane function, and thermodynamic stability in living organisms. Our literature review provides the basis for the presentation of a novel hypothesis as to the origin of endogenous bio-sulfates which involves energy transduction from sunlight. Our hypothesis is amply supported by a growing body of data showing that parenteral administration of substances that lower serum zeta potential results in kosmotropic cationic and/or chaotropic anionic interfacial water stress, and the resulting cascade.
http://www.mdpi.com/1099-4300/14/8/1399 (Also view full text from that link by clicking full study)
Warning to Pregnant Mothers - Toxic Dose of Aluminum in the Tdap, Pediatrician Paul Thomas (same video as at the top of page)
https://www.youtube.com/watch?v=VoY6vXEMsU8
Aluminum in Vaccines | A Pediatricians Warning To All Parents (same video as at the bottom of page)
https://www.youtube.com/watch?v=ee70I5bm3-k
The Initial Common Pathway of Inflammation, Disease, and Sudden Death, (full study source)
Pay particular attention to reading pages, Page 414-415 in regard to vaccine aluminum adjuvants, and as well pages 419-420 in regard to Gardasil.
Excerpted:
Page 414-415
The respiratory and auditory centers [218,219] in the brainstem are vulnerable to microvascular ischemic stress. So too is the pancreas [220–225]. Watershed and terminal vascular distributions are particularly susceptible to microvascular ischemic stress [223–225]. These vascular distributions would
be predicted to be highly susceptible to pathologic inflammatory stimulation and thrombohemorrhagic phenomena [3] induced by zeta potential-lowering and interfacial water stress-inducing properties of cationic kosmotropic electrolytes and polyelectrolyte surfactants. Dr Mohammed Al-Bayati’s
histopathologic analyses of SIDS [220–222] and so-called Shaken Baby Syndrome (SBS) victims [226] are most informative. Al-Bayati’s work provides strong support for the view that microvascular ischemia plays a central role in the pathophysiology of SIDS and, by inference, all SDS events [220–222]. Surfactant induced water stress [29,40,43,45,54,174,178,211,212] especially that associated with polycationic surfactants, is an important determinant of risk. Risk factors for SDS are synergistic and cumulative.
Expressed most simply, anything that perturbs the ZP toward less negative values and/or induces cationic kosmotropic or anionic chaotropic water stress represents a step in the direction of enzyme inhibition, protein dysfunction, cellular dysfunction, flocculation, gelation, coagulation,
microvascular ischemia, cellular anoxia, infarction, and death.
Transcytosis, both endocytosis and exocytosis, membrane potentials [219,227], and ion channels are all profoundly disrupted by polycationic surfactants [31,89,228–231]. A very relevant example is aluminum (Al3+), a kosmotropic trivalent cation, which is a potent and irreversible blocker of voltage activated calcium channels in mammalian neurons [31,228]. Ca-ATPase, protein kinase C and calmodulin (CaM) are biological systems known to be disrupted by aluminum [37,87,178,232]. Another very relevant example is mercury (Hg2+), a kosmotropic divalent cation. It has been shown in infant monkeys that the ethylmercury in thimerosal is more readily stored as inorganic mercury (Hg2+) in the brain than is orally-delivered ethylmercury and that inorganic mercury tends to linger longer in the tissues [231].
Thus, the sudden death syndrome can now be defined as an acute disruption of the colloidal stability of the vascular system, which triggers a cascade of events [97–100,229,230] leading to death, whenever compensatory mechanisms to maintain colloidal stability of the blood are insufficient. If compensatory mechanisms are sufficient, the cascade can instead lead to a new equilibrium. Mucopolysaccharides, also known as glycosaminoglycans (GAGs), contribute to the inflammatory state of the Shwartzman phenomenon [233–236]. Upon exposure to systemic stress, increases in sulfomucopolysaccharide incorporation occur throughout the body, and this is designated as the “universal nonspecific mesenchymal reaction” [3].
Gardasil
Page 419-420
2.9. Acute Shock and Role of Endothelial NOS-derived NO in SDS
Anaphylactic shock is a sudden, life-threatening allergic reaction associated with severe hypotension. Platelet-activating factor (PAF) is implicated in the cardiovascular dysfunctions occurring in various shock syndromes, including anaphylaxis. Anaphylactic shock is especially associated with quadrivalent HPV vaccine, which contains aluminum hydroxide. Based on the number of confirmed cases, the estimated rate of anaphylaxis following quadrivalent HPV vaccine was
significantly higher than identified in comparable school-based delivery of other vaccines [282].
In this review, we have described several of the adverse biophysical properties associated with cationic surfactants, Al3+ salts, and non-ionic surfactants. The U.S. CDC VAERS database provides considerable evidence of life threatening anaphylactic shock and anaphylactoid events associated with HPV vaccine, as well as with all of the aluminum (3+) containing vaccines, some of which resulted in sudden death. The U.S. CDC Vaccine Excipient & Media Summary states, “Excipients are inactive ingredients of a drug product necessary for production of a finished pharmaceutical formulation.” In the February 2012 update, the CDC disclosed that excipients in U.S. HPV vaccine include amorphous aluminum hydroxyphosphate sulfate, polysorbate 80, and sodium borate (from the manufacturer’s package insert of March, 2011). The relevance to SDS is apparent from reports of unexplained deaths of some women attributed to HPV vaccines in the CDC VAERS database, some of which were described variably as death during sleep or while bathing.
A reasonable question should be raised as to the purported safety and alleged biologic inactivity of the ingredients in the HPV vaccine, particularly aluminum, polysorbate 80, and sodium borate. Moreover, a further reasonable question should be Entropy 2012, 14 1420 raised as to the purported safety and alleged biologic inactivity of all of the aluminum and polysorbate 80 containing vaccines. This question may be further explored by analysis of the CDC VAERS database.
For example, CDC VAERS report ID: 337242 states “my daughter had her 3rd GARDASIL vaccine in Sept. She was a very healthy young lady, she went to take a shower and died. Autopsy report states undermined [undetermined] death. There was no sign of trauma to the body to indicate a fall. She had pointed the shower head away from her and she got down on her knees and put her head on the edge of the tub and passed away.”
Sources: http://www.mdpi.com/1099-4300/14/8/1399
http://people.csail.mit.edu/seneff/Entropy/Entropy1_downloaded.pdf
Stephanie Seneff
http://www.informatik.uni-trier.de/~ley/pers/hy/s/Seneff:Stephanie.html
Gardasil: New Study Brings More Safety Questions to Light
By Norma Erickson, President
Excerpts:
Why were HPV-16 L1 DNA fragments detected in post mortem samples taken six months after Gardasil vaccination and not the other vaccine-relevant types? Dr. Sin Hang Lee, of Milford Hospital and Milford Molecular Laboratory, may have provided an answer in his most recently published paper entitled, Topological conformational changes of human papillomavirus (HPV) DNA bound to an insoluble aluminum salt – A study by low temperature PCR.[1] His findings suggest that non-B-conformational changes in HPV L1 gene DNA fragments bound to the AAHS adjuvant may be genotype related, in other words specific to HPV-16.
In September 2011, SaneVax Inc. informed the FDA that despite all claims stating Gardasil contained ‘no viral DNA’ Dr. Lee had discovered there were indeed fragments of HPV-11, HPV-16 and HPV-18 L1 DNA firmly attached to Merck’s proprietary aluminum adjuvant in 100% of the samples he tested, but all were lacking a region amplifiable by an MY09 degenerate primer.[2] The FDA was quick to confirm that Gardasil does contain residual HPV L1 gene DNA fragments,[3] but that these fragments posed no health risk. The FDA completely ignored a request for further investigations put forth by the SaneVax Team.[4]
In light of the FDA statement corroborating Dr. Lee’s previous findings, the presence of HPV DNA fragments of vaccine origin in the bodies of recipients might be anticipated after intramuscular injections of Gardasil. However, finding HPV-16 L1 DNA fragments in post-mortem blood samples of a teenager who died six months after completion of 3 Gardasil injections without finding any other vaccine-relevant fragments was a surprise.[5] Obviously, further investigations were necessary.
At the request of SaneVax Inc., Dr. Lee agreed to use PCR amplification followed by direct DNA sequencing to try and determine what was going on. What he discovered is stated clearly in the conclusion of the above referenced paper. It says:
Where does this leave the average medical consumer? Unfortunately, it leaves them with the following unanswered questions:
Once injected, how long will the HPV-16 L1 DNA fragments attached to aluminum remain in my body?
Are the non-B conformation HPV fragments in Gardasil potentially harmful?
Will the non-B conformation DNA fragments in Gardasil induce autoimmune disorders?
Will the non-B conformation DNA get integrated in the genome causing mutagenesis and/or cancer?
The scientific community needs to investigate these potential risks immediately. Medical consumers need to know the risks as well as any potential benefits before they decide if Gardasil is right for them.
In the interest of public health and safety, the FDA needs to rescind approval for Gardasil until satisfactory answers are provided to the four questions above. The time for poke and hope is long since passed. Medical consumers need proof this vaccine is safe.
Read more:
http://sanevax.org/gardasil-new-study-brings-more-safety-questions-to-light/
Death after Quadrivalent Human Papillomavirus (HPV) Vaccination: Causal or Coincidental?
Conclusions: Our study suggests that HPV vaccines containing HPV-16L1 antigens pose an inherent risk for
triggering potentially fatal autoimmune vasculopathies.
http://www.rescuepost.com/files/ltshaw-death-after-quadrivalent-hpv-vaccination-pharma-reg-affairs-2012.pdf
The Potential Significance of Aluminum/DNA Compounds in Gardasil on Health
http://sanevax.org/the-potential-significance-of-aluminumdna-compounds-in-gardasil-on-health/
The persistence of HPV DNA fragments and adverse effects in HPV shot recipients
http://www.examiner.com/article/the-persistence-of-hpv-dna-fragments-and-adverse-effects-hpv-shot-recipients
Gardasil: Are you paying for your own bullet?
The temperature of the heated controversy concerning Gardasil was recently raised even more when Dr. Bernhard Dalbergue (France), former pharmaceutical industry physician with Merck, recently predicted that the vaccine will become the greatest medical scandal of all times.
In an interview in the April 2014 issue (no. 66) of the magazine Principes de Santé (Health Principles), Dr. Dalbergue, who has worked for over twenty years with the industry, describes the widespread corruption and his concern that the health of patients is sacrificed on the altar of profitability.
Dr. Dalbergue stated:
I predict that Gardasil will become the greatest medical scandal of all times because at some point in time, the evidence will add up to prove that this vaccine has absolutely no effect on cervical cancer and that all the very many adverse effects which destroy lives and even kill, serve no other purpose than to generate profit for the manufacturers.
According to Dr. Dalbergue the pharmaceutical industry has hardened considerably during the last decade, as shown by increased violations of ethics, manipulation of clinical trial data, widespread corruption, gross conflicts of interest and generally less emphasis on pharmacovigilance.
Read more:
http://sanevax.org/gardasil-paying-for-your-own-bullet/
Why is neurotoxic aluminum in vaccines, (Over 600 mcg in all three shots of Gardasil. The brand name Cervarix now showing equally as harmful, with its new APo4 adjuvant). http://en.wikipedia.org/wiki/Cervarix
Excerpt:
Aluminum hydroxide is a neurotoxic poison
This form of aluminum is a protoplasmic poison and a potent neurotoxin that is completely unnatural to the biochemical process of any life form on earth. The American Academy of Pediatrics has stated that aluminum is now being implicated as interfering with a variety of cellular and metabolic processes in the nervous system and other tissues. Aluminum toxicity is known to cause encepthalitis, bone disease and anemia.
“Aluminum hydroxide is used in vaccines to increase the body’s production of antibodies, though no one knows how it works,” says Purdue researcher Stanley Hem, professor of industrial and physical pharmacy.
Antigens are protein molecules that stimulate the immune system. Antibodies are protein molecules made by the immune system to defend against foreign substances. In the 1930’s, vaccine researchers tested a number of ingredients to see what would effectively bring antigens into the body so the immune system of the individual would produce antibodies.
Aluminum was proved to be an effective adjuvant or substance that irritates the immune system and causes antibody production.
Read more:
http://www.naturalhealth365.com/vaccine_dangers/toxic_aluminum.html
Gardasil-The Real Truth
http://www.vacfacts.info/gardasil---the-real-truth.html
09 Andrew Moulden En 07 de 11
http://www.youtube.com/watch?v=8hUOVChsJ9w
09 Andrew Moulden En 06 de 11
http://www.youtube.com/watch?v=58KLLm1q0_Y
Vaccination toxicity: The Zeta phase of MASS and “blood sludging”
http://www.vacfacts.info/vaccination-toxicity-the-zeta-phase-of-mass-and-ldquoblood-sludgingrdquo.html
TOXICOLOGICAL PROFILE FOR ALUMINUM
http://www.atsdr.cdc.gov/ToxProfiles/tp22.pdf
----------------
Crit Rev Toxicol. 2014 Oct;44 Suppl 4:1-80. doi: 10.3109/10408444.2014.934439.
Systematic review of potential health risks posed by pharmaceutical, occupational and consumer exposures to metallic and nanoscale aluminum, aluminumoxides, aluminum hydroxide and its soluble salts.
Willhite CC1, Karyakina NA, Yokel RA, Yenugadhati N, Wisniewski TM, Arnold IM, Momoli F, Krewski D.
Abstract
Abstract Aluminum (Al) is a ubiquitous substance encountered both naturally (as the third most abundant element) and intentionally (used in water, foods, pharmaceuticals, and vaccines); it is also present in ambient and occupational airborne particulates. Existing data underscore the importance of Al physical and chemical forms in relation to its uptake, accumulation, and systemic bioavailability. The present review represents a systematic examination of the peer-reviewed literature on the adverse health effects of Al materials published since a previous critical evaluation compiled by Krewski et al. (2007) . Challenges encountered in carrying out the present review reflected the experimental use of different physical and chemical Al forms, different routes of administration, and different target organs in relation to the magnitude, frequency, and duration of exposure. Wide variations in diet can result in Al intakes that are often higher than the World Health Organization provisional tolerable weekly intake (PTWI), which is based on studies with Al citrate. Comparing daily dietary Al exposures on the basis of "total Al"assumes that gastrointestinal bioavailability for all dietary Al forms is equivalent to that for Al citrate, an approach that requires validation. Current occupational exposure limits (OELs) for identical Al substances vary as much as 15-fold. The toxicity of different Al forms depends in large measure on their physical behavior and relative solubility in water. The toxicity of soluble Al forms depends upon the delivered dose of Al(+3) to target tissues. Trivalent Al reacts with water to produce bidentate superoxide coordination spheres [Al(O2)(H2O4)(+2) and Al(H2O)6 (+3)] that after complexation with O2(•-), generate Al superoxides [Al(O2(•))](H2O5)](+2). Semireduced AlO2(•) radicals deplete mitochondrial Fe and promote generation of H2O2, O2 (•-) and OH(•). Thus, it is the Al(+3)-induced formation of oxygen radicals that accounts for the oxidative damage that leads to intrinsic apoptosis. In contrast, the toxicity of the insoluble Al oxides depends primarily on their behavior as particulates. Aluminum has been held responsible for human morbidity and mortality, but there is no consistent and convincing evidence to associate the Al found in food and drinking water at the doses and chemical forms presently consumed by people living in North America and Western Europe with increased risk for Alzheimer's disease (AD). Neither is there clear evidence to show use of Al-containing underarm antiperspirants or cosmetics increases the risk of AD or breast cancer. Metallic Al, its oxides, and common Al salts have not been shown to be either genotoxic or carcinogenic. Aluminum exposures during neonatal and pediatric parenteral nutrition (PN) can impair bone mineralization and delay neurological development. Adverse effects to vaccines with Al adjuvants have occurred; however, recent controlled trials found that the immunologic response to certain vaccines with Al adjuvants was no greater, and in some cases less than, that after identical vaccination without Al adjuvants. The scientific literature on the adverse health effects of Al is extensive. Health risk assessments for Al must take into account individual co-factors (e.g., age, renal function, diet, gastric pH). Conclusions from the current review point to the need for refinement of the PTWI, reduction of Al contamination in PN solutions, justification for routine addition of Al to vaccines, and harmonization of OELs for Al substances.
http://www.ncbi.nlm.nih.gov/pubmed/25233067
Immunotherapy. 2014;6(10):1055-71. doi: 10.2217/imt.14.81.
Are there negative CNS impacts of aluminum adjuvants used in vaccines and immunotherapy?
Shaw CA1, Li D, Tomljenovic L.
Abstract
In spite of a common view that aluminum (Al) salts are inert and therefore harmless as vaccine adjuvants or in immunotherapy, the reality is quite different. In the following article we briefly review the literature on Al neurotoxicity and the use of Al salts as vaccine adjuvants and consider not only direct toxic actions on the nervous system, but also the potential impact for triggering autoimmunity. Autoimmune and inflammatory responses affecting the CNS appear to underlie some forms of neurological disease, including developmental disorders. Al has been demonstrated to impact the CNS at every level, including by changing gene expression. These outcomes should raise concerns about the increasing use of Al salts as vaccine adjuvants and for the application as more general immune stimulants.
http://www.ncbi.nlm.nih.gov/pubmed/25428645
Biotech Histochem. 2015 Feb;90(2):132-9. doi: 10.3109/10520295.2014.965277. Epub 2014 Oct 14.
A histological study of toxic effects of aluminium sulfate on rat hippocampus.
Çabuş N1, Oğuz EO, Tufan AÇ, Adıgüzel E.
Abstract
Aluminium has toxic effects on many organ systems of the human body. Aluminium toxicity also is a factor in many neurodegenerative diseases. We investigated changes in numbers of hippocampal neurons in rats exposed to aluminium using an optical fractionator and we investigated aluminium-induced apoptosis using the transferase mediated dUTP nick end labeling (TUNEL) assay. Twenty-four female rats were divided equally into control, sham and aluminium-exposed groups. The control group received no treatment. The two treatment groups were injected intraperitoneally with 1 ml 0.9% saline without (sham) and with 3 mg/ml aluminium sulfate every day for two weeks. Following the treatments, the brains were removed, the left hemisphere was used for hippocampal neuron counting using an optical fractionator and the right hemisphere was investigated using hippocampal TUNEL assay to determine the apoptotic index. The number of neurons in the stratum pyramidale of the hippocampus was significantly less in the aluminium group than in the control and sham groups; there was no significant difference between the control and sham groups. The apoptotic index also was significantly higher in the aluminium group than in the other two groups. We quantified the toxic effects of aluminium on the rat hippocampus and determined that apoptosis was the mechanism of aluminium-induced neuron death in the hippocampus.
http://www.ncbi.nlm.nih.gov/pubmed/25314162
Int J Alzheimers Dis. 2011 Mar 8;2011:276393. doi: 10.4061/2011/276393.
Link between Aluminum and the Pathogenesis of Alzheimer's Disease: The Integration of the Aluminum and Amyloid Cascade Hypotheses.
Kawahara M1, Kato-Negishi M.
Abstract
Whilst being environmentally abundant, aluminum is not essential for life. On the contrary, aluminum is a widely recognized neurotoxin that inhibits more than 200 biologically important functions and causes various adverse effects in plants, animals, and humans. The relationship between aluminum exposure and neurodegenerative diseases, including dialysis encephalopathy, amyotrophic lateral sclerosis and Parkinsonism dementia in the Kii Peninsula and Guam, and Alzheimer's disease (AD) has been suggested. In particular, the link between aluminum and Alzheimer's disease has been the subject of scientific debate for several decades. However, the complex characteristics of aluminum bioavailability make it difficult to evaluate its toxicity and therefore, the relationship remains to be established. Mounting evidence has suggested that significance of oligomerization of β-amyloid protein and neurotoxicity in the molecular mechanism of AD pathogenesis. Aluminum may play crucial roles as a cross-linker in β-amyloid oligomerization. Here, we review the detailed characteristics of aluminum neurotoxicity based on our own studies and the recent literatures. Our aim is to revisit the link between aluminum and AD and to integrate aluminum and amyloid cascade hypotheses in the context of β-amyloid oligomerization and the interactions with other metals.
http://www.ncbi.nlm.nih.gov/pubmed/21423554
J Trace Elem Med Biol. 2012 Oct;26(4):291-3. doi: 10.1016/j.jtemb.2012.02.005. Epub 2012 Mar 15.
Aluminium overload after 5 years in skin biopsy following post-vaccination with subcutaneous pseudolymphoma.
Guillard O1, Fauconneau B, Pineau A, Marrauld A, Bellocq JP, Chenard MP.
Abstract
Aluminium hydroxide is used as an effective adjuvant in a wide range of vaccines for enhancing immune response to the antigen. The pathogenic role of aluminium hydroxide is now recognized by the presence of chronic fatigue syndrome, macrophagic myofasciitis and subcutaneous pseudolymphoma, linked to intramuscular injection of aluminium hydroxide-containing vaccines. The aim of this study is to verify if the subcutaneous pseudolymphoma observed in this patient in the site of vaccine injection is linked to an aluminium overload. Many years after vaccination, a subcutaneous nodule was discovered in a 45-year-old woman with subcutaneous pseudolymphoma. In skin biopsy at the injection site for vaccines, aluminium (Al) deposits are assessed by Morin stain and quantification of Al is performed by Zeeman Electrothermal Atomic Absorption Spectrophotometry. Morin stain shows Al deposits in the macrophages, and Al assays (in μg/g, dry weight) were 768.10±18 for the patient compared with the two control patients, 5.61±0.59 and 9.13±0.057. Given the pathology of this patient and the high Al concentration in skin biopsy, the authors wish to draw attention when using the Al salts known to be particularly effective asadjuvants in single or repeated vaccinations. The possible release of Al may induce other pathologies ascribed to the well-known toxicity of this metal.
http://www.ncbi.nlm.nih.gov/pubmed/22425036
----------------
Etiology: An Editorial on the Prevention of Communication Disorders
Excerpt: In the field of communication disorders, perhaps the most neglected area in the scope of practice of speech-language pathologists and audiologists is prevention [5]. Yet to prevent disorders it is necessary first and foremost to seek out their causes. Let this editorial serve as a call for papers seeking out causes with a view toward prevention. The work can be guided in part, at least, by the sure knowledge that all disorders, disease conditions, and even death itself involve breakdowns in the biological control systems that enable health and well-being. Understanding the disruptive factors that cause such breakdowns [6] will go a long way toward enabling their prevention. Also we know now for a certainty that certain environmental toxins are causally involved [7].
http://www.esciencecentral.org/journals/etiology-an-editorial-on-the-prevention-of-communication-disorders-JCDSHA.e101.php?aid=15245
Michigan doctor reveals plan to stop autism
April is National Autism Awareness Month and the Centers for Disease Control (CDC) now estimates that one in 68 children has been identified with autism spectrum disorder (ASD). The rates have increased 30% since the reported estimate of one in 88 two years ago. The rate was one in 10,000 in 1970.
A physician, Dr. Marvin Anderson, has been treating children with ASD in his clinic at Abba’s Place since 2009. He has written a book entitled Autism Prevention, Care and Management. In his book, Dr. Anderson describes his experiences helping children with autism and attention deficit hyperactivity disorder (ADHD) and he proposes a positive and hopeful solution to ending the autism epidemic that is spreading throughout the world. His treatment for ASD and ADHD is primarily directed to the digestive tract, including the liver. Animal studies have shown an intriguing connection between inflammation in the intestinal tract and inflammation in the brain. Autism also can involve impairments in the body’s detoxification pathways. Dr. Anderson’s program includes identifying contaminants that are present in his patients and creating a detoxification plan for their safe and efficient removal. Inflammation elsewhere in the body, including the brain, is also addressed. An important part of this plan involves care of the liver using the principles of liver cleansing advanced by Dr. Sandra Cabot in her best-selling book, The Liver Cleansing Diet.
Dr. Anderson has discussed his plan for ending the autism epidemic in detail with state of Michigan Representative Ray Franz. The plan consists of enacting three laws by the state legislature.
I. Require that all newborn infants receive an autism prevention screening test prior to receiving any vaccinations. The “one size fits all” approach to vaccinations is no longer working. According to Dr. Gregory Poland et al. in Vaccinomics and Personalized Vaccinology, included in the 2012 Jordan Report, Accelerated development of vaccines, “...significant individual variation exists in risk of adverse events and in immune response to a given vaccine.
Read more:
http://www.examiner.com/article/michigan-doctor-reveals-plan-to-stop-autism
THE BOOK: Autism Prevention Care and Management
Written by a physician with 10 year’s experience caring for children with this calamity – summarizes the problem and solution to the epidemic of autism that is spreading throughout the world.
http://www.autismatabbasplace.com/book.html
Phenotypic expression of autoimmune autistic disorder (AAD): A major subset of autism
Vijendra K. Singh, PhD
Brain State International Research Center, Scottsdale, AZ, USA
BACKGROUND: Autism causes incapacitating neurologic problems in children that last a lifetime. The author of this article previously hypothesized that autism may be caused by autoimmunity to the brain, possibly triggered by a viral infection. This article is a summary of laboratory findings to date plus new data in support of an autoimmune pathogenesis for autism.
METHODS: Autoimmune markers were analyzed in the sera of autistic and normal children, but the cerebrospinal fluid (CSF) of some autistic children was also analyzed. Laboratory procedures included enzyme-linked immunosorbent assay and protein immunoblotting assay.
RESULTS: Autoimmunity was demonstrated by the presence of brain autoantibodies, abnormal viral serology, brain and viral antibodies in CSF, a positive correlation between brain autoantibodies and viral serology, elevated levels of proinflammatory cytokines and acute-phase reactants, and a positive response to immunotherapy. Many autistic children harbored brain myelin basic protein autoantibodies and elevated levels of antibodies to measles virus and measles-mumps-rubella (MMR) vaccine. Measles might be etiologically linked to autism because measles and MMR antibodies (a viral marker) correlated positively to brain autoantibodies (an autoimmune marker)—salient features that characterize autoimmune pathology in autism. Autistic children also showed elevated levels of acute-phase reactants—a marker of systemic inflammation.
CONCLUSION: The scientific evidence is quite credible for our autoimmune hypothesis, leading to the identification of autoimmune autistic disorder (AAD) as a major subset of autism. AAD can be identified by immune tests to determine immune problems before administering immunotherapy. The author has advanced a speculative neuroautoimmune (NAI) model for autism, in which virus-induced autoimmunity is a key player. The latter should be targeted by immunotherapy to help children with autism.
https://www.aacp.com/Pages.asp?AID=7937
Is Encephalopathy a Mechanism to Renew Sulfate in Autism?
Stephanie Seneff 1,*, Ann Lauritzen 2 , Robert M. Davidson 3 and Laurie Lentz-Marino 4
Entropy; Jan2013, Vol. 15 Issue 1, p372
ABSTRACT This paper makes two claims: (1) autism can be characterized as a chronic lowgrade encephalopathy, associated with excess exposure to nitric oxide, ammonia and glutamate in the central nervous system, which leads to hippocampal pathologies and resulting cognitive impairment, and (2), encephalitis is provoked by a systemic deficiency in sulfate, but associated seizures and fever support sulfate restoration. We argue that impaired synthesis of cholesterol sulfate in the skin and red blood cells, catalyzed by sunlight and nitric oxide synthase enzymes, creates a state of colloidal instability in the blood manifested as a low zeta potential and increased interfacial stress. Encephalitis, while life-threatening, can result in partial renewal of sulfate supply, promoting neuronal survival. Research is cited showing how taurine may not only help protect neurons from hypochlorite exposure, but also provide a source for sulfate renewal. Several environmental factors can synergistically promote the encephalopathy of autism, including the herbicide, glyphosate, aluminum, mercury, lead, nutritional deficiencies in thiamine and zinc, and yeast overgrowth due to excess dietary sugar. Given these facts, dietary and lifestyle changes, including increased sulfur ingestion, organic whole foods, increased sun exposure, and avoidance of toxins such as aluminum, mercury, and lead, may help to alleviate symptoms or, in some instances, to prevent autism altogether.
http://www.mdpi.com/1099-4300/15/1/372
Autism: A neuroepigenetic disorder, By Richard C. Deth, PhD
http://www.autismone.org/sites/default/files/Deth_ASD03.pdf
Empirical Data Confirm Autism Symptoms Related to Aluminum and Acetaminophen Exposure
Stephanie Seneff, Robert M. Davidson, and Jingjing Liu
http://www.mdpi.com/1099-4300/14/11/2227
http://people.csail.mit.edu/seneff/Entropy/entropy-14-02227.pdf
GLUTATHIONE Scientific Research
Our findings suggest that acetaminophen administration selectively depletes (within 2 hr) mitochondrial glutathione, and produces local toxicity by altering membrane permeability and decreasing the efficiency of oxidative phosphorylation. This renders mitochondria more susceptible to oxidative damage… PMID: 8937421
http://www.readisorb.com/science/glutathione_scientific_researc.html
Biochem Pharmacol. 1996 Oct 25;52(8):1147-54.
Effect of acetaminophen administration on hepatic glutathione compartmentation and mitochondrial energy metabolism in the rat.
http://www.ncbi.nlm.nih.gov/pubmed/8937421
Scientific Research, 2nd Page
http://www.readisorb.com/science/
Tim Guilford, MD
Glutathione in Health and Disease
http://www.svhi.com/newsletters/2005/slf-122005.pdf
Glutathione
http://www.readisorb.com/
Glutathione, Tylenol, Vaccine Adverse Reactions, and ASD
http://www.vacfacts.info/glutathione-tylenol-vaccine-adverse-reactions-and-asd.html
Neurodegenerative Diseases: Neurotoxins as Sufficient Etiologic Agents?
Christopher A. Shaw and Günter U. Höglinger
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2814816/
Neuroscience and Biobehavioral Reviews
Analysis of neurological disease in four dimensions: insight from ALS-PDC epidemiology and animal models
The causal factor(s) responsible for sporadic neurological diseases are unknown and the stages of disease progression remain undefined and poorly understood. We have developed an animal model of amyotrophic lateral sclerosis-parkinsonism dementia complex which mimics all the essential features of the disease with the initial neurological insult arising from neurotoxins contained in washed cycad seeds. Animals fed washed cycad develop deficits in motor, cognitive, and sensory behaviors that correlate with the loss of neurons in specific regions of the central nervous system. The ability to recreate the disease by exposure to cycad allows us to extend the model in multiple dimensions by analyzing behavioral, cellular, and biochemical changes over time. In addition, the ability to induce toxin-based neurodegeneration allows us to probe the interactions between genetic and epigenetic factors. Our results show that the impact of both genetic causal and susceptibility factors with the cycad neurotoxins are complex. The article describes the features of the model and suggests ways that our understanding of cycad-induced neurodegeneration can be used to decipher and identify the early events in various human neurological diseases.
http://yadda.icm.edu.pl/yadda/element/bwmeta1.element.elsevier-a4f127e4-0c75-3f6d-bb32-9406a3136a76
And to realize that in any of the studies that the CDC has considered as to vaccine toxicity, none of that has been studied, and nor as well has any basic physiological science like this been addressed nor even acknowledged. They are yet by CHOICE, in the dark ages, as to their known and accepted knowledge, and of the human body, and its immune system
Dr Blaylock, a Board-certified neurosurgeon, Visiting Professor of Biology at Belhaven College, Jackson, Mississippi, and member of the Editorial Board of the Journal of the American Nutraceutical Association (JANA), is the author of three books on excitotoxicity: Excitoxicity: the taste that kills, Health and nutrition secrets, and Natural strategies for cancer patients.
EXCITOTOXICITY: A POSSIBLE CENTRAL MECHANISM IN FLUORIDE NEUROTOXICITY, (the fluoride and aluminum connection)
by Russell L Blaylocka, Ridgeland, MS, USA
SUMMARY: Recent evidence indicates that fluoride produces neuronal destruction and synaptic injury by a mechanism that involves free radical production and lipid peroxidation. For a number of pathological disorders of the central nervous system (CNS), excitotoxicity plays a critical role. Various studies have shown that many of the neurotoxic metals, such as mercury, lead, aluminum, and iron also injure neural elements in the CNS by an excitotoxic mechanism. Free radical generation and lipid peroxidation, especially in the face of hypomagnesemia and low neuronal energy production, also magnify excitotoxic sensitivity of neurons and their elements. This paper reviews briefly some of the studies that point to a common mechanism for the CNS neurotoxic effects of fluoride and calls for research directed toward further elucidation of this mechanism.
http://www.fluorideresearch.org/374/files/374301-314.pdf
Dr Andrew Wakefield Defends His Research, (a quite lengthy video, but puts the TRUTH front and center, all of it).
https://www.youtube.com/watch?v=i6DuBR_xGQg
Vaccine Safety Conference Session 15 Dr. Andrew Wakefield
http://www.youtube.com/watch?v=8Ei0QSvKdgw
http://www.vaccinesafetyconference.com/videos.html#WakefieldVideo
Selective Hearing: Brian Deer and the GMC
http://topdocumentaryfilms.com/selective-hearing-brian-deer-and-the-gmc/
Research References, (endless, and all of it is ignored by the CDC)
http://www.callous-disregard.com/research.htm
Dr Andrew Wakefield - MMR Vaccine - Truth and Reality
http://www.vacfacts.info/dr-andrew-wakefield---mmr-vaccine---truth-and-reality.html
------------
Journal of the Neurological Sciences
Volume 280, Issues 1–2, 15 May 2009, Pages 101–108
Biomarkers of environmental toxicity and susceptibility in autism
Abstract
Autism spectrum disorders (ASDs) may result from a combination of genetic/biochemical susceptibilities in the form of a reduced ability to excrete mercury and/or increased environmental exposure at key developmental times. Urinary porphyrins and transsulfuration metabolites in participants diagnosed with an ASD were examined. A prospective, blinded study was undertaken to evaluate a cohort of 28 participants with an ASD diagnosis for Childhood Autism Rating Scale (CARS) scores, urinary porphyrins, and transsulfuration metabolites. Testing was conducted using Vitamin Diagnostics, Inc. (CLIA-approved) and Laboratoire Philippe Auguste (ISO-approved). Participants with severe ASDs had significantly increased mercury intoxication-associated urinary porphyrins (pentacarboxyporphyrin, precoproporphyrin, and coproporphyrin) in comparison to participants with mild ASDs, whereas other urinary porphyrins were similar in both groups. Significantly decreased plasma levels of reduced glutathione (GSH), cysteine, and sulfate were observed among study participants relative to controls. In contrast, study participants had significantly increased plasma oxidized glutathione (GSSG) relative to controls. Mercury intoxication-associated urinary porphyrins were significantly correlated with increasing CARS scores and GSSG levels, whereas other urinary porphyrins did not show these relationships. The urinary porphyrin and CARS score correlations observed among study participants suggest that mercury intoxication is significantly associated with autistic symptoms. The transsulfuration abnormalities observed among study participants indicate that mercury intoxication was associated with increased oxidative stress and decreased detoxification capacity.
http://www.sciencedirect.com/science/article/pii/S0022510X08004310
Mitochondrial Dysfunction in Autism
Context Impaired mitochondrial function may influence processes highly dependent on energy, such as neurodevelopment, and contribute to autism. No studies have evaluated mitochondrial dysfunction and mitochondrial DNA (mtDNA) abnormalities in a well-defined population of children with autism.
Main Outcome Measures Oxidative phosphorylation capacity, mtDNA copy number and deletions, mitochondrial rate of hydrogen peroxide production, and plasma lactate and pyruvate.
Conclusion In this exploratory study, children with autism were more likely to have mitochondrial dysfunction, mtDNA overreplication, and mtDNA deletions than typically developing children.
Autism spectrum disorders (ASD) are characterized by impaired social interaction, problems with verbal and nonverbal communication, and repetitive or severely restricted activities and interests.1 Limited scientific advances have been made regarding the causes of autism, with general agreement that both genetic and environmental factors contribute to this disorder.
Some reports have suggested that mitochondrial dysfunction and altered energy metabolism may influence the social and cognitive deficits in autism2- 4; however, most reports involved only 1 or a few isolated cases.2,5 A school-based study of 69 children aged 10 to 14 years with confirmed autism or ASD found mitochondrial respiratory chain dysfunction in 7.2%.4 Considering the limitations of elevated lactate-to-pyruvate ratios and the bias toward skeletal muscle disturbances in the study sample, some cases were likely overlooked, and the incidence in the affected population could actually be higher than reported. To our knowledge, there are no systematic studies aimed at investigating changes in mitochondrial function, mitochondrial DNA (mtDNA) copy number, mtDNA deletions, and oxidative stress in children with autism who have been clinically well defined.
Mitochondrial function in disease often has been investigated in muscle biopsies6; however, the detection of mitochondrial defects in readily available cells from body fluids (lymphocytes and platelets7) would be valuable under the assumption that many such defects may not be confined to muscle or the brain, tissues in which mitochondrial diseases are most strongly evident. Considering that the energy requirement for lymphocytes is derived almost equally from glycolysis and oxidative phosphorylation,8 we tested the hypothesis that children with full syndrome autism have dysfunctional mitochondria in peripheral blood lymphocytes.
Objective To evaluate mitochondrial defects in children with autism.
Read more:
http://jama.ama-assn.org/content/304/21/2389.abstract
Unvaccinated Children Will Be Healthiest Among Future Generations Studies and Surveys Predict
http://www.fhfn.org/unvaccinated-children-will-be-healthiest-among-future-generations-studies-and-surveys-predict/
Vaccine Truth Informational Brochures:
Do not allow all of the vaccine-injured childrens injuries to be in vain. Educate others in honor of them. Be the Voice for those who don't have one. Do not be silent. You can inform other parents. We provide multiple free brochures you can give to educate other parents.
Download and print them now.
http://www.educate4theinjured.org/eric/4571993523
Educate Others: (Three brochures)
http://www.educate4theinjured.org/eric/4571993523#!brochures/cee5
CURRENT VACCINE SCHEDULE- 26 DOSES BEFORE THE 1ST YEAR OF LIFE. 49 DOSES BY AGE 6. Do you have your 49 doses? Nope, NEITHER DO I, OR HER OR HIM. Look around you. Who has had the 49 doses we give our children? OUR CHILDHOOD VACCINES HAVE ALREADY WANED! SINCE AROUND 90% OF ADULTS ARE CONSIDERED UNVACCINATED, WHY ARENT WE HAVING EPIDEMICS? Are so many vaccines safe?
Is Aborted Fetal DNA in Vaccines Linked to Autism?
The vaccine-autism connection was first hypothesized following the introduction of a new measles, mumps and rubella (MMR) vaccine to the U.S. in 1979, with complete U.S. market share by 1983, and to the UK in 1988. Autism rates began to rise in the U.S. after 1979 and rose dramatically after 1983, and likewise rose in the UK after 1988, leading physicians to suspect a link. Initially, the measles component of this vaccine, MMR II, was suspected to be the culprit. Subsequent studies have also focused on the presence of mercury in vaccines, which incidentally, the MMR II vaccine did not contain.
Those studies have largely ruled out the new measles portion of the MMR II or mercury as the environmental trigger for autism. However, the compelling temporal association between this new MMR vaccine and autism cannot be ignored or explained away. What has been ignored is the fact that this new MMR vaccine introduced the use of aborted fetal cells for vaccine production. At one point, as much as 94 percent of children in the U.S. and 98 percent of children in the UK were given this vaccine.
Today, more than 23 vaccines are contaminated by the use of aborted fetal cells. There is no law that requires that consumers be informed that some vaccines are made using aborted fetal cells and contain residual aborted fetal DNA. While newer vaccines produced using aborted fetal cells do inform consumers, in their package inserts, that the vaccines contain contaminating DNA from the cell used to produce the vaccine, they do not identify the cells as being derived from electively aborted human fetuses.
In other words, they tell you what is in the vaccine, but they don’t fully inform you where it came from. The earliest aborted fetal cell-produced vaccines such as Meruvax (rubella) and MMR II do not even inform consumers that the vaccines contain contaminating DNA from the cell used to produce them. Furthermore, it is unconscionable that the public-health risk of injecting our children with residual contaminating human aborted fetal DNA has been ignored.
How could the contaminating aborted fetal DNA create problems? It creates the potential for autoimmune responses and/or inappropriate insertion into our own genomes through a process called recombination. There are groups researching the potential link between this DNA and autoimmune diseases such as juvenile (type I) diabetes, multiple sclerosis and lupus. Our organization, [3] Sound Choice Pharmaceutical Institute (SCPI), is focused on studying the quantity, characteristics and genomic recombination of the aborted fetal DNA found in many of our vaccines.
Read more: http://www.physiciansforlife.org/content/view/1758/2/
http://media.wix.com/ugd/c2b39a_6c6beca3ffbb4c249b3bb66cb55eb307.pdf
-------------------
“Aluminum is an experimentally demonstrated neurotoxin and the most commonly used vaccine adjuvant. Despite almost 90 years of widespread use of aluminum adjuvants, medical science's understanding about their mechanisms of action is still remarkably poor. There is also a concerning scarcity of data on toxicology and pharmacokinetics of these compounds. In spite of this, the notion that aluminum in vaccines is safe appears to be widely accepted.
Experimental research, however, clearly shows that aluminum adjuvants have a potential to induce serious
immunological disorders in humans. In particular, aluminum in adjuvant form carries a risk for autoimmunity, long-term brain inflammation and associated neurological complications and may thus have profound and widespread adverse health consequences. In our opinion, the possibility that vaccine benefits may have been overrated and the risk of potential adverse effects underestimated, has not been rigorously evaluated in the medical and scientific community”
Aluminum vaccine adjuvants: are they safe? [Curr Med Chem. 2011] - PubMed - NCBI
http://www.ncbi.nlm.nih.gov/pubmed/21568886
BE AWARE OF THE DELAYED REACTION!
HOW LONG AFTER A VACCINE DO INJURIES OCCUR?
IMMEDIATELY TO YEARS LATER.
OFTEN 13-19 DAYS AFTER VACCINATION.
YOU KNOW THE SCREAMS
Arched back. Inconsolable crying. ENCEPHALITIS. BRAIN DAMAGE. Many parents do not recognize the link between
vaccination and reaction or injury because often times the reaction is delayed until after the vaccine virus incubates. Almost a month after they get their shots. This takes up to and around 3-4 weeks after the child is injected to occur. WATCH YOUR BABY AROUND THE 2ND-3RD WEEK! KEEP THEM CLOSE TO YOU! COMFORT THEM IF THEY BECOME SICK. NO TYLENOL OR ADVIL. THIS HURTS THE DETOXIFICATION PROCESS AND PUTS YOUR BABY AT GREATER RISK FOR SEIZURES.
"There is insufficient evidence to support routine vaccination of healthy persons of any age. - Paul Frame, M.D., Journal of Family Practice"
"My suspicion, which is shared by others in my profession, is that the nearly 10,000 SIDS deaths that occur in the United States each year are related to one or more of the vaccines that are routinely given children. The pertussis vaccine is the most likely villain, but it could also be one or more of the others." --Dr.
Mendelsohn, M.D.
"The evidence for indicting immunizations for SIDS is circumstantial, but compelling. However, the keepers of the keys to medical-research funds are not interested in researching this very important lead to the cause of an ongoing, and possibly preventable, tragedy. Anything that implies that immunizations are not the greatest medical advance in the history of public health is ignored or ridiculed. Can you imagine the economic and political import of discovering that immunizations are killing thousands of babies?" --Dr. Douglass M.D.
Crib death was so infrequent in the prevaccine era that it was not even mentioned in the statistics, but it started to climb in the 1950s with the spread of mass vaccination against diseases of childhood. --
Harris L.Coulter, PhD."
Read more:
http://media.wix.com/ugd/c2b39a_03f8aac260f54057bd33359c4ec6c03c.pdf
Memorial to Victims of the Silent War ~ VACCINES ~
Cease for Peace! ~ Interviews with Sallie O. Elkordy
http://billiontoddlermarchforsurvival.blogspot.com/
5 Reasons Not To Get The Flu Shot:
http://vaccineresistancemovement.org/?p=12642
VRM: The Problem With Vaccines Part 4 – Primary Aspects of Vaccine Toxicity Affecting The Body
http://vaccineresistancemovement.org/?p=8787
--------------
Review of Vaccine Induced Immune Overload and the Resulting Epidemics of
Type 1 Diabetes and Metabolic Syndrome, Emphasis on Explaining the Recent
Accelerations in the Risk of Prediabetes and other Immune Mediated Diseases
J Barthelow Classen MD
3637 Rockdale Road, Manchester, MD 21102, USA
Abstract
There has been an epidemic of inflammatory diseases that has paralleled the epidemic on iatrogenic immune stimulation with vaccines. Extensive evidence links vaccine induced immune over load with the epidemic of type 1 diabetes. More recent data indicates that obesity, type 2 diabetes and other components of metabolic syndrome are highly associated with immunization and may be manifestations of the negative feedback loop of the immune system
reacting to the immune overload. The epidemic of diabetes/prediabetes appears to be accelerating at a time when the prevalence of obesity has stabilized, indicating that the negative feedback system of the immune system has been over whelmed. The theory of vaccine induced immune overload can explain the key observations that have confounded many competing hypothesis. The current paper reviews the evidence that vaccine induced immune overload explains the disconnect between the increase in prediabetes and nonalcoholic fatty liver at a time when the obesity epidemic is waning in children.
http://www.vaccines.net/vaccine-induced-immune-overload.pdf
Vaccine-induced immune overload now affects majority of US children, study finds.
Read article here: http://www.thelibertybeacon.com/?p=21474
---------------------
A Parent’s Primer: Vasculitis and Vaccines, (more inflammation problems, likely due to the aluminum adjuvants, this time its in the blood vessels)
http://sanevax.org/a-parents-primer-vasculitis-and-vaccines/
How the aluminum adjuvants cause this said inflammation.
J Immunol. 2008 Sep 15;181(6):3755-9. Cutting edge: alum adjuvant stimulates inflammatory dendritic cells through activation of the NALP3 inflammasome.
http://www.ncbi.nlm.nih.gov/pubmed/18768827
Hypothesis Neuro-inflammation, blood-brain barrier, seizures and autism
http://www.jneuroinflammation.com/content/8/1/168
Research The NALP3 inflammasome is involved in neurotoxic prion peptide-induced microglial activation
http://www.jneuroinflammation.com/content/9/1/73/abstract
BRAIN’S IMMUNE SYSTEM TRIGGERED IN AUTISM, (and clueless of them there is of course no mention proposed causation nor vaccines, while sitting right on the smoking gun. Same findings though, without even a thought nor mention of causation )
http://www.hopkinsmedicine.org/Press_releases/2004/11_15a_04.html
Ann Neurol. 2005 Jan;57(1):67-81. Neuroglial activation and neuroinflammation in the brain of patients with autism.
Vargas DL, Nascimbene C, Krishnan C, Zimmerman AW, Pardo CA.
Source: Department of Neurology, Johns Hopkins University School of Medicine, 600 North Wolfe Street, Baltimore, MD 21287, USA.
http://www.neuro.jhmi.edu/neuroimmunopath/pdf/4%20Neuroglial%20activation%20and%20neuroinflammation%20in%20the%20brain%20of%20patients%20with%20autism.pdf
http://www.ncbi.nlm.nih.gov/pubmed/15546155
A couple more examples exist below.
Nanomolar aluminum induces pro-inflammatory and pro-apoptotic gene expression in human brain cells in primary culture
http://www.sciencedirect.com/science/article/pii/S0162013405001182
http://www.ncbi.nlm.nih.gov/pubmed/15961160
Microglial Activation and Increased Microglial Density Observed in the Dorsolateral Prefrontal Cortex in Autism
www.anthro.ucsd.edu/faculty-staff/profiles/files/Morgan_2010.pdf
http://www.sciencedirect.com/science/article/pii/S000632231000497X
http://www.ncbi.nlm.nih.gov/pubmed/20674603
Microglial Activation and Increased Microglial Density Observed in the Dorsolateral Prefrontal Cortex in Autism, (with a list of other related studies)
http://www.journalogy.net/Publication/35542161/microglial-activation-and-increased-microglial-density-observed-in-the-dorsolateral-prefrontal
Immunity, neuroglia and neuroinflammation in autism
http://www.journalogy.net/Publication/6149686/immunity-neuroglia-and-neuroinflammation-in-autism
Blood-brain barrier flux of aluminum, manganese, iron and other metals suspected to contribute to metal-induced neurodegeneration, (and they are injecting newborn infants with hepatitis B vaccine containing an aluminum adjuvant which is recklessly for profit insane)
http://www.ncbi.nlm.nih.gov/pubmed/17119290
Nanomaterials can be transported by monocyte-lineage cells to DLNs, blood and spleen, and, similarly to HIV, may use CCL2-dependent mechanisms to penetrate the brain. This occurs at a very low rate in normal conditions explaining good overall tolerance of alum despite its strong neurotoxic potential. However, continuously escalating doses of this poorly biodegradable adjuvant in the population may become insidiously unsafe, especially in the case of overimmunization or immature/altered blood brain barrier or high constitutive CCL-2 production.
http://www.ncbi.nlm.nih.gov/pubmed/23557144
http://www.biomedcentral.com/1741-7015/11/99
Empirical Data Confirm Autism Symptoms Related to Aluminum and Acetaminophen Exposure
http://people.csail.mit.edu/seneff/Entropy/entropy-14-02227.pdf
How much proof, and as well scientific study proof, would you and should you need? Nothing would be enough, is the attitude of those in the so called medical field and regulatory fields, (and with everything to lose, the truth be known).
The Vaccine Truth-Facts
https://www.youtube.com/watch?v=r0y2t01mqvI
WE DON'T VACCINATE! Myth And Reality Of Vaccination Campaigns (Trailer)
https://www.youtube.com/watch?v=t2cc5J7vlOg&feature=youtu.be
10 Facts Vaccine Companies Don't Want You to Know!
https://www.youtube.com/watch?v=7yqtu9TRi7A
The CDC has to know this. Yet, they're trying to make you believe that if you don't vaccinate your child you're endangering the health of other children. But nothing could be farther from the truth. All the science conducted by independent researchers shows that vaccines can harm your children and grandchildren. This is not some conspiracy theory; it's scientific fact.
http://www.burtongoldberg.com/vaccines.html#.VSBgIDL5Viw.facebook
Dr. Chris Shaw discusses the toxic side effects of Aluminum in Vaccines. Oct-21-2009
This is enough information and from Suzanne Humphries should be in itself enough to shut down the entire CDC directed infant vaccination schedule. But you know that again they will ignore it; and because not to would obviously finish them entirely.
Suzanne Humphries, MD - Neonatal Immunity: The first 3 years of life: (the above video)
“Nothing should interfere with the immunologic programming, especially during the first three years.” Normal brain development depends on the baby maintaining a non-inflammatory state. Vaccines drive excessive inflammation and can derail normal brain development:
https://www.youtube.com/watch?v=wL8srdLw4c0
Dr. Suzanne Humphries Has A Lot To Say About Aluminum In Vaccines
“By the age of 18 months, that infant has already received 4,925 micrograms (mcg) of aluminum, 100 percent of which is absorbed since it’s given intramuscularly. In the 1980s the amount of aluminum you got when following the childhood vaccination schedule amounted to 1,120 mcg, and importantly, it was given in more mature babies, not newborns. Today, American children end up getting a grand total of 6,150 mcg of aluminum if they get all of their recommended vaccines.”
Read more:
http://www.collective-evolution.com/2015/04/20/dr-suzanne-humphries-has-a-lot-to-say-about-aluminum-in-vaccines/
Dr Suzanne Humphries. Aluminum is toxic to all life forms: The case against aluminum in vaccines. (the above video)
https://youtu.be/LZe99K12740
Vaccination: The Neurological Poison So Common Your Doctor Probably Pushes It
http://articles.mercola.com/sites/articles/archive/2012/04/11/vaccination-impact-on-childrens-health.aspx
Dr. Paul Offit’s Aluminum Deceptions and Academic Misconduct (one very important article, to read)
http://vaccinepapers.org/dr-paul-offits-aluminum-deceptions-academic-misconduct/
The Defense of Aluminum Adjuvant, Debunked
http://vaccinepapers.org/rigorous-defense-al-adjuvant-wrong/
Part 1: Immune Activation and Autism
http://vaccinepapers.org/rigorous-defense-al-adjuvant-wrong/
See all posts on Immune Activation
Part 1: Immune Activation and Autism
Part 2: Interleukin-6 and Autism
Part 3: Monkey Experiments
Part 4: (Coming Soon) Prenatal vs. Postnatal Immune Activation
http://vaccinepapers.org/immune-activation/
Scientific Papers Library
Immune Activation
http://vaccinepapers.org/scientific-papers-library/
A More Rigorous Defense of Al Adjuvant, and Why it is Wrong
http://vaccinepapers.org/rigorous-defense-al-adjuvant-wrong/
VRM: The Problem With Vaccines Part 2 – Synergistic Effect of Heavy Metal Toxicity On The Body
http://vaccineresistancemovement.org/?p=6097
The Mechanisms of Vaccine Injury and Via Cytokine Storm
http://www.vacfacts.info/the-mechanisms-of-vaccine-injury-and-via-cytokine-storm.html
Vaccination toxicity: The Zeta phase of MASS and “blood sludging”
http://www.vacfacts.info/vaccination-toxicity-the-zeta-phase-of-mass-and-ldquoblood-sludgingrdquo.html
Unvaccinated Children Will Be Healthiest Among Future Generations Studies and Surveys Predict
http://www.fhfn.org/unvaccinated-children-will-be-healthiest-among-future-generations-studies-and-surveys-predict/
Journal of Toxicology- Aluminum
Volume 2009 (2009), Article ID 532640,
http://dx.doi.org/10.1155/2009/532640
Published Research
Aluminum Vacciune Adjuvants
Mercury - Neurological and Immune Development
http://www.cmsri.org/published-research/
J Expo Sci Environ Epidemiol. 2010 Nov;20(7):598-601. doi: 10.1038/jes.2009.64. Epub 2009 Dec 16.
Infants' exposure to aluminum from vaccines and breast milk during the first 6 months.
Dórea JG1, Marques RC.
Abstract
The success of vaccination programs in reducing and eliminating infectious diseases has contributed to an ever-increasing number of vaccines given at earlier ages (newborns and infants). Exposure to low levels of environmental toxic substances (including metals) at an early age raises plausible concerns over increasingly lower neuro-cognitive rates. Current immunization schedules with vaccines containing aluminum (as adjuvant) are given to infants, but thimerosal (as preservative) is found mostly in vaccines used in non-industrialized countries. Exclusively, breastfed infants (in Brazil) receiving a full recommended schedule of immunizations showed an exceedingly high exposure of Al (225 to 1750 μg per dose) when compared with estimated levels absorbed from breast milk (2.0 μg). This study does not dispute the safety of vaccines but reinforces the need to study long-term effects of early exposure to neuro-toxic substances on the developing brain. Pragmatic vaccine safety needs to embrace conventional toxicology, addressing especial characteristics of unborn fetuses, neonates and infants exposed to low levels of aluminum, and ethylmercury traditionally considered innocuous to the central nervous system.
http://www.ncbi.nlm.nih.gov/pubmed/20010978
Tox-Guide For Aluminum-Al
http://www.atsdr.cdc.gov/toxguides/toxguide-22.pdf
Int J Alzheimers Dis. 2011 Mar 8;2011:276393. doi: 10.4061/2011/276393.
Link between Aluminum and the Pathogenesis of Alzheimer's Disease: The Integration of the Aluminum and Amyloid Cascade Hypotheses.
Kawahara M1, Kato-Negishi M.
Abstract
Whilst being environmentally abundant, aluminum is not essential for life. On the contrary, aluminum is a widely recognized neurotoxin that inhibits more than 200 biologically important functions and causes various adverse effects in plants, animals, and humans. The relationship between aluminum exposure and neurodegenerative diseases, including dialysis encephalopathy, amyotrophic lateral sclerosis and Parkinsonism dementia in the Kii Peninsula and Guam, and Alzheimer's disease (AD) has been suggested. In particular, the link between aluminum and Alzheimer's disease has been the subject of scientific debate for several decades. However, the complex characteristics of aluminum bioavailability make it difficult to evaluate its toxicity and therefore, the relationship remains to be established. Mounting evidence has suggested that significance of oligomerization of β-amyloid protein and neurotoxicity in the molecular mechanism of AD pathogenesis. Aluminum may play crucial roles as a cross-linker in β-amyloid oligomerization. Here, we review the detailed characteristics of aluminum neurotoxicity based on our own studies and the recent literatures. Our aim is to revisit the link between aluminum and AD and to integrate aluminum and amyloid cascade hypotheses in the context of β-amyloid oligomerization and the interactions with other metals.
http://www.ncbi.nlm.nih.gov/pubmed/21423554
Review Article
Aluminum-Induced Entropy in Biological Systems:
Implications for Neurological Disease
5. Conclusions
Aluminuminducesentropyinlivingorganismsbydisrupting
all levels of structure from water molecules through all
biosemiotic systems. Entropy-inducing cascades, feedback
loops (positive and negative) within and across levels, can
damage DNAs, RNAs, proteins, cells, tissues, and whole organ
systems. As a result of cellular damage caused by an
Al compound, injured and dying cells will release proteases,
excitatory amino acids, and ions (e.g., potassium, calcium),
disrupting biosemiosis at many levels. Toxic effects of Al and
its compounds thus tend to proliferate. Interactive results
involving immune functions, for instance, make the impact
worse than if only one system were involved. Of course, the
dose-response of Al and its compounds must be considered,
but even at low doses, especially with repeated exposures, Al
can have cumulative deleterious effects that can be extreme
and even fatal. For that reason, a repeated low dose exposure
may prove more damaging than a single larger dose. Al
and its compounds can cross biosemiotic levels, damaging
genetic systems, proteins, cells, and all systems up through
the CNS. While higher doses may rapidly affect multiple
levels, as in dialysis-associated encephalopathy (DAE), low
doses over time, for example, from vaccines, can degrade
metabolism and disrupt repair and defense systems and can
spiraloutofcontrolasinASIA.Aladjuvantsinvaccinesmay
hyperdrive the immune functions of the body but they also
directly disrupt biosemiotic systems. Sound theory, empirical
research, and reasonable inferences from sources cited here
show that Al and its compounds damage biological systems.
Such conclusions warrant considerations at a policy level to
limit human exposure to Al and its compounds
Read more:
http://people.csail.mit.edu/seneff/Shaw_et_al_JOT_2014.pdf
Treatment Manual for HPV Vaccine Injured
http://vaccineimpact.com/2015/treatment-manual-for-hpv-vaccine-injured/
Mass Vaccine Brainwashing Campaign Exposed
https://www.youtube.com/watch?feature=player_detailpage&v=S9HwpHDHFWo&app=desktop
How To Recognize the Signs And Symptoms of Vaccine Reactions
http://www.nvic.org/Downloads/4507NVIC11x17HIRES.aspx
Is Aluminum The New Thimerosal?
http://sarahjmuma.files.wordpress.com/2012/05/aluminum-new-thimerosal-sears.pdf
Research Article
The Severity of Autism Is Associated with Toxic Metal Body Burden and Red Blood Cell Glutathione Levels
Abstract
This study investigated the relationship of children's autism symptoms with their toxic metal body burden and red blood cell (RBC) glutathione levels. In children ages 3–8 years, the severity of autism was assessed using four tools: ADOS, PDD-BI, ATEC, and SAS. Toxic metal body burden was assessed by measuring urinary excretion of toxic metals, both before and after oral dimercaptosuccinic acid (DMSA). Multiple positive correlations were found between the severity of autism and the urinary excretion of toxic metals. Variations in the severity of autism measurements could be explained, in part, by regression analyses of urinary excretion of toxic metals before and after DMSA and the level of RBC glutathione (adjusted of 0.22–0.45, in all cases). This study demonstrates a significant positive association between the severity of autism and the relative body burden of toxic metals.
http://www.hindawi.com/journals/jt/2009/532640/ (full study)
Aluminum Induced Immunoexcitotoxicity in Neurodevelopmental and Neurodegenerative Disorders
Russell L. Blaylock*
Visiting Professor Biology Belhaven University Theoretical Neurosciences Research, LLC Ridgeland, Mississippi, USA
Abstract
A great deal has been learned about the neurotoxicity of aluminum over the past two decades in terms of its ability to disrupt cellular function. Newer evidence suggests that a more central pathophysiological mechanism may be responsible for much of the toxicity of aluminum and aluminofluoride compounds on the brain. This mechanism involves activation of the brainâ € ™ s innate immune system, primarily the microglia, with a release of neurotoxic concentrations of excitotoxins and pro-inflammatory cytokines, chemokines and immune mediators. A large number of studies suggest that excitotoxicity plays a significant role in the neurotoxic action of a number of metals, including aluminum. Recently, researchers have found that while most of the chronic neurodegenerative effects of these metals are secondary to prolonged inflammation, it is the enhancement of excitotoxicity by the immune mediators that is responsible for most of the metalâ € ™ s toxicity. This enhancement occurs via a crosstalk between cytokine receptors and glutamate receptors. The author coined the name immunoexcitotoxicity to describe this process. This paper reviews the evidence linking immunoexcitotoxicity to aluminums neurotoxic effects.
http://www.geoengineeringwatch.org/documents/Aluminum-Blaylock.pdf
Aluminum Induced Immunoexcitotoxicity in Neurodevelopmental and Neurodegenerative Disorders
http://chiropractorwestpalmbeach.net/2013/06/27/aluminum-induced-immunoexcitotoxicity-in-neurodevelopmental-and-neurodegenerative-disorders/
Raising A Vaccine Free Child, by Wendy Lydall
http://www.vaccinefreechild.com/
Fight Autism and Win! By parents for parents! (the Andy Cutler chelation protocol)
http://www.fightautismandwin.com/#sthash.XITmXJsq.dpbs
http://www.amazon.com/Fight-Autism-Win-Biomedical-Therapies/dp/0615582095
Autism, ADD, ADHD: 2014
“What’s Really Working?”
Featuring Amy Derksen, ND
With bonus lecture by Dietrich Klinghardt, MD. PHD
http://www.klinghardtacademy.com/images/stories/event/autism_add_adhd_whats_working_today.pdf
J Inorg Biochem. 2013 No;128:237-44. doi: 10.1016/j.jinorgbio.2013.07.022. Epub 2013 Jul 19.
Administration of aluminium to neonatal mice in vaccine-relevant amounts is associated with adverse long term neurological outcomes.
Shaw CA1, Li Y, Tomljenovic L.
Abstract
Our previous ecological studies of autism spectrum disorder (ASD) has demonstrated a correlation between increasing ASD rates and aluminium (Al) adjuvants in common use in paediatric vaccines in several Western countries. The correlation between ASD rate and Al adjuvant amounts appears to be dose-dependent and satisfies 8 of 9 Hill criteria for causality. We have now sought to provide an animal model to explore potential behavioural phenotypes and central nervous system (CNS) alterations using s.c. injections of Al hydroxide in early postnatal CD-1 mice of both sexes. Injections of a "high" and "low" Al adjuvant levels were designed to correlate to either the U.S. or Scandinavian paediatric vaccine schedules vs. control saline-injected mice. Both male and female mice in the "high Al" group showed significant weight gains following treatment up to sacrifice at 6 months of age. Male mice in the "high Al" group showed significant changes in light-dark box tests and in various measures of behaviour in an open field. Female mice showed significant changes in the light-dark box at both doses, but no significant changes in open field behaviours. These current data implicate Al injected in early postnatal life in some CNS alterations that may be relevant for a better understanding of the aetiology of ASD.
© 2013.
http://www.ncbi.nlm.nih.gov/pubmed/23932735
Exposure to Mercury and Aluminum in Early Life: Developmental Vulnerability as a Modifying Factor in Neurologic and Immunologic Effects
Abstract: Currently, ethylmercury (EtHg) and adjuvant-Al are the dominating interventional exposures encountered by fetuses, newborns, and infants due to immunization with Thimerosal-containing vaccines (TCVs). Despite their long use as active agents of medicines and fungicides, the safety levels of these substances have never been determined, either for animals or for adult humans—much less for fetuses, newborns, infants, and children. I reviewed the literature for papers reporting on outcomes associated with (a) multiple exposures and metabolism of EtHg and Al during early life; (b) physiological and metabolic characteristics of newborns, neonates, and infants relevant to xenobiotic exposure and effects; (c) neurobehavioral, immunological, and inflammatory reactions to Thimerosal and Al-adjuvants resulting from TCV exposure in infancy. Immunological and neurobehavioral effects of Thimerosal-EtHg and Al-adjuvants are not extraordinary; rather, these effects are easily detected in high and low income countries, with co-exposure to methylmercury (MeHg) or other neurotoxicants. Rigorous and replicable studies (in different animal species) have shown evidence of EtHg and Al toxicities. More research attention has been given to EtHg and findings have showed a solid link with neurotoxic effects in humans; however, the potential synergic effect of both toxic agents has not been properly studied. Therefore, early life exposure to both EtHg and Al deserves due consideration.
http://www.mdpi.com/1660-4601/12/2/1295/htm
Journal of American Nutraceutical Association 6: 21-35, 2003.
Interaction of Cytokines, Excitotoxins, and Reactive Nitrogen and Oxygen Species in Autism Spectrum Disorders, Russell Blaylock, MD* Medical Director, Advanced Nutritional Concepts Ridgeland, Mississippi
ABSTRACT
There is growing and compelling evidence that excessive peripheral as well as central immune activation of brain microglia can result in alterations in brain growth and connectivity during rapid brain growth, the so-called "brain growth spurt." A considerable amount of evidence, presented in this paper, demonstrates the deleterious effects of immune factors, such as cytokines, chemokines, and excitotoxins, when present in excess. The interaction between excitotoxicity, ROS and RNS injury and immune dysfunction is discussed. It is concluded that excessive activation of the brain's immune system during critical growth periods can occur when vaccines are given as combination vaccines, using schedules that are too close together or by the use of certain live viruses in the vaccines.
http://www.nutrimedical.com/news.jhtml?method=view&news.id=1084
Recent Changes In Vaccines
"They’ve been increasing the amount of aluminum in vaccines quite systematically particularly over the last 10 years,” says Dr. Stephanie Seneff, senior scientist at MIT who has been conducting research for over three decades. She is considered the leading expert on sulfur and how it functions in the body. She is an electrical engineer, a computer science specialist who then converted into the biological sciences with a biology degree as well as a food and nutrition specialty.
“They’ve been increasing the number of vaccines as well. I’m deeply disturbed by what I’m seeing,” she says. The root of her worry is, “They add the aluminum in order to get the child to react enough. If the child has a strong immune system and you just give them a vaccine of some dead microbe, the body’s going to slough it off – they won’t actually be resistant to the disease. They have to put something else in the vaccine to make you react more. They’ve discovered that aluminum works really well.” At the same time it’s causing all the trouble.
Read more:
http://nourishingplot.com/2014/06/27/recent-changes-in-vaccines/
The Mechanisms of Vaccine Injury and Via Cytokine Storm
http://www.vacfacts.info/the-mechanisms-of-vaccine-injury-and-via-cytokine-storm.html
Although this next study does not involve vaccines; if you follow the studies on these pages, you will realize how similar the same type of vaccine injury is, to traumatic brain injury; and it clearly involves the same or similar physiological and biological systems.
Surg Neurol Int. 2011; 2: 107.
Published online 2011 July 30. doi: 10.4103/2152-7806.83391
PMCID: PMC3157093
Immunoexcitotoxicity as a central mechanism in chronic traumatic encephalopathy—A unifying hypothesis
Published online 2011 July 30. doi: 10.4103/2152-7806.83391
PMCID: PMC3157093
Russell L. Blaylock* and Joseph Maroon1
Abstract
Some individuals suffering from mild traumatic brain injuries, especially repetitive mild concussions, are thought to develop a slowly progressive encephalopathy characterized by a number of the neuropathological elements shared with various neurodegenerative diseases. A central pathological mechanism explaining the development of progressive neurodegeneration in this subset of individuals has not been elucidated. Yet, a large number of studies indicate that a process called immunoexcitotoxicity may be playing a central role in many neurodegenerative diseases including chronic traumatic encephalopathy (CTE). The term immunoexcitotoxicity was first coined by the lead author to explain the evolving pathological and neurodevelopmental changes in autism and the Gulf War Syndrome, but it can be applied to a number of neurodegenerative disorders. The interaction between immune receptors within the central nervous system (CNS) and excitatory glutamate receptors trigger a series of events, such as extensive reactive oxygen species/reactive nitrogen species generation, accumulation of lipid peroxidation products, and prostaglandin activation, which then leads to dendritic retraction, synaptic injury, damage to microtubules, and mitochondrial suppression. In this paper, we discuss the mechanism of immunoexcitotoxicity and its link to each of the pathophysiological and neurochemical events previously described with CTE, with special emphasis on the observed accumulation of hyperphosphorylated tau.
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3157093/
Download PDF: Immunoexcitotoxicity as a central mechanism in chronic traumatic encephalopathy-A unifying hypothesis
http://www.surgicalneurologyint.com/downloadpdf.asp?issn=2152-7806%3Byear%3D2011%3Bvolume%3D2%3Bissue%3D1%3Bspage%3D107%3Bepage%3D107%3Baulast%3DBlaylock%3Btype%3D2
Session 22, The Vaccine Safety Conference: Dr. Russell Blaylock, MD, CCN
THE CENTRAL ROLE OF IMMUNOEXCITOTOXICITY IN ALUMINUM AND MERCURY-CONTAINING ADJUVANT-TRIGGERED NEURODEVELOPMENTAL AND NEURODEGENERATIVE DISORDERS
http://www.youtube.com/watch?v=u9DkcpEEBPI
Dr. Russell Blaylock, MD, CCN, video presentation -(same video as above, for an alternate source).
http://www.vaccinesafetyconference.com/videos.html#BlaylockVideo
How Vaccines Harm Child Brain Development - Dr Russell Blaylock MD
http://www.youtube.com/watch?v=7QBcMYqlaDs
Vaccination and brain inflammation
http://www.heartmdinstitute.com/prevention/immunity/vaccinations/167-vaccines-depression-neurodegeneration-after-age-50-years?showall=&
Danger of live virus vaccines
http://www.heartmdinstitute.com/prevention/immunity/vaccinations/167-vaccines-depression-neurodegeneration-after-age-50-years?showall=&
A Mechanism of Toxicity of Aluminium-based Adjuvants?
Consumer Summary | by Chris Exley
http://www.vaccinesafetyconference.com/exley
Exley & House (2011) Aluminium in the human brain. Monatsh Chem (In press)
http://www.springerlink.com/content/9550512205128414/
Aluminum as a Neurotoxin: The Evidence from Cell Culture, In Vivo, & Human Studies
http://www.vaccinesafetyconference.com/pdf/Shaw/Shaw_PPT.pdf
Study Reveals Children are Being Vaccinated With Toxic Levels of Aluminium Causing Neurological Damage & Autism
A recent study conducted by Canadian scientists Professor Christopher Shaw and Dr. Lucija Tomljenovic revealed that the more vaccines that children receive containing the adjuvant aluminum, the greater their chance is of developing autism, autoimmune diseases and neurological problems in the future.
In 2013, in their paper, published by Springer Science+Business Media, titled Aluminum in the Central Nervous System: Toxicity in Humans and Animals, Vaccine Adjuvants, and Autoimmunity, they revealed that during a 17-year period, the rates of autism had increased significantly in countries that had the most vaccinations containing the adjuvant aluminum.
A Highly Significant Correlation
The researchers compared the number of vaccines recommend by the Centers for Disease Control and Prevention (CDC) during the period from 1991 – 2008 and the changes in the autism rates during the same period. They wrote:
“The data sets, graphed against each other, show a pronounced and statistically highly significant correlation between the number vaccines with aluminum and the changes in autism rates. Further data showed that a significant correlation exists between the amounts of aluminum given to preschool children and the current rates of autism in seven Western countries. Those countries with the highest level of aluminum-adjuvanted vaccines had the highest autism rates.” [1] (own emphasis)
Read more:
http://www.thelibertybeacon.com/2014/06/23/study-reveals-children-are-being-vaccinated-with-toxic-levels-of-aluminium-causing-neurological-damage-autism/
Dr. Chris Shaw discusses the toxic side effects of Aluminum in Vaccines. Oct-21-2009, (very informative)
https://www.youtube.com/watch?v=LsAKoRx60xs
Review of Vaccine Induced Immune Overload and the Resulting Epidemics of
Type 1 Diabetes and Metabolic Syndrome, Emphasis on Explaining the Recent
Accelerations in the Risk of Prediabetes and other Immune Mediated Diseases
Abstract
There has been an epidemic of inflammatory diseases that has paralleled the epidemic on iatrogenic immune
stimulation with vaccines. Extensive evidence links vaccine induced immune over load with the epidemic of type 1
diabetes. More recent data indicates that obesity, type 2 diabetes and other components of metabolic syndrome are
highly associated with immunization and may be manifestations of the negative feedback loop of the immune system
reacting to the immune overload. The epidemic of diabetes/prediabetes appears to be accelerating at a time when
the prevalence of obesity has stabilized, indicating that the negative feedback system of the immune system has
been over whelmed. The theory of vaccine induced immune overload can explain the key observations that have
confounded many competing hypothesis. The current paper reviews the evidence that vaccine induced immune
overload explains the disconnect between the increase in prediabetes and nonalcoholic fatty liver at a time when the obesity epidemic is waning in children.
http://vaccines.net/vaccine-induced-immune-overload.pdf
Do aluminum vaccine adjuvants contribute to the rising prevalence of autism?
Lucija Tomljenovic a, Christopher A. Shaw a,b
http://pop.1796kotok.com/pdfs/Aluminum_autism.pdf
DR. CHRIS SHAW: ALUMINUM IN THE BODY - ONE MORE GIRL EXCERPTS
http://www.youtube.com/watch?v=FfTo35UrFPA
Abstract for talk: Aluminum as a neurotoxin: the evidence from cell culture, in vivo, and
human studies
http://www.vaccinesafetyconference.com/pdf/Shaw/Shaw_CS.pdf
Autism Spectrum Disorders and Aluminum Vaccine Adjuvants
Lucija Tomljenovic, Russell L. Blaylock, Christopher A. Shaw
Abstract
Impaired brain function, excessive inflammation, and autoimmune manifestations are common in autism. Aluminum (Al), the most commonly used vaccine adjuvant, is a demonstrated neurotoxin and a strong immune stimulator. Hence, adjuvant Al has the necessary properties to induce neuroimmune disorders. Because peripheral immune stimuli in the postnatal period can compromise brain development and cause permanent neurological impairments, the possibility that such outcomes could also occur with administration of Al vaccine adjuvants needs to be considered. In regard to the risk of adjuvant toxicity in children, the following should be noted: (i) children should not be viewed as “small adults” as their unique physiology makes them more vulnerable to toxic insults; (ii) in adult humans Al adjuvants can cause a variety of serious autoimmune and inflammatory conditions including those affecting the brain, yet children are routinely exposed to much higher amounts of Al from vaccines than adults; (iii) compelling evidence has underscored the tight connection between the development of the immune system and that of the brain. Thus, it appears plausible that disruptions of critical events in immune development may also play a role in the establishment of neurobehavioral disorders; (iv) the same immune system components that play key roles in brain development appear to be targeted for impairment by Al adjuvants. In summary, research data suggests that vaccines containing Al may be a contributing etiological factor in the increasing incidence of autism.
http://link.springer.com/referenceworkentry/10.1007%2F978-1-4614-4788-7_89
Alzheimers
Int J Alzheimers Dis. 2012;2012:914947. doi: 10.1155/2012/914947. Epub 2012 Jul 30.
Cognitive deterioration and associated pathology induced by chronic low-level aluminum ingestion in a translational rat model provides an explanation of Alzheimer's disease, tests for susceptibility and avenues for treatment.
Walton JR.
Abstract
A translational aging rat model for chronic aluminum (Al) neurotoxicity mimics human Al exposure by ingesting Al, throughout middle age and old age, in equivalent amounts to those ingested by Americans from their food, water, and Al additives. Most rats that consumed Al in an amount equivalent to the high end of the human total dietary Al range developed severe cognitive deterioration in old age. High-stage Al accumulation occurred in the entorhinal cortical cells of origin for the perforant pathway and hippocampal CA1 cells, resulting in microtubule depletion and dendritic dieback. Analogous pathological change in humans leads to destruction of the perforant pathway and Alzheimer's disease dementia. The hippocampus is thereby isolated from neocortical input and output normally mediated by the entorhinal cortex. Additional evidence is presented that Al is involved in the formation of neurofibrillary tangles, amyloid plaques, granulovacuolar degeneration, and other pathological changes of Alzheimer's disease (AD). The shared characteristics indicate that AD is a human form of chronic Al neurotoxicity. This translational animal model provides fresh strategies for the prevention, diagnosis, and treatment of AD.
http://www.ncbi.nlm.nih.gov/pubmed/22928148
NEW STUDY REVEALS CHILDREN BEING VACCINATED WITH TOXIC LEVELS OF ALUMINUM CAUSING NEUROLOGICAL DAMAGE AND AUTISM
In their landmark 2013 paper, Canadian scientists Professor Christopher Shaw and Dr. Lucija Tomljenovic show that the more children receive vaccines with aluminum adjuvants, the greater their chance is of developing autism, autoimmune diseases and neurological problems later in life. A demonstrated neurotoxin, Aluminum is the only approved adjuvant in the US. Its use presents the risk of brain inflammation, autoimmunity and other adverse health consequences.
http://www.fhfn.org/new-study-reveals-children-being-vaccinated-with-toxic-levels-of-aluminum-causing-neurological-damage-and-autism/
Immunol Res. 2013 Jul;56(2-3):304-16. doi: 10.1007/s12026-013-8403-1.
Aluminum in the central nervous system (CNS): toxicity in humans and animals, vaccine adjuvants, and autoimmunity.
http://www.ncbi.nlm.nih.gov/pubmed/23609067
Administration of aluminium to neonatal mice in vaccine-relevant amounts is associated with adverse long term neurological outcomes
C.A. Shawa,b,c, ⁎, Y. Li a , L. Tomljenovic a
Abstract:
Our previous ecological studies of autism spectrum disorder (ASD) has demonstrated a correlation between increasing ASD rates and aluminium (Al) adjuvants in common use in paediatric vaccines in several Western countries. The correlation between ASD rate and Al adjuvant amounts appears to be dose-dependent and satisfies 8 of 9 Hill criteria for causality. We have now sought to provide an animal model to explore potential behavioural phenotypes and central nervous system (CNS) alterations using s.c. injections of Al hydroxide in early postnatal CD-1 mice of both sexes. Injections of a “high” and “low”Al adjuvant levels were designed to correlate to either the U.S. or Scandinavian paediatric vaccine schedules vs. control saline-injected mice. Both male and female mice
in the “high Al” group showed significant weight gains following treatment up to sacrifice at 6 months of age. Male mice in the “high Al” group showed significant changes in light–dark box tests and in various measures of behaviour in an open field. Female mice showed significant changes in the light–dark box at both doses, but no significant changes in open field behaviours. These current data implicate Al injected in early postnatal life in some CNS alterations that may be relevant for a better understanding of the aetiology of ASD. © 2013 Elsevier Inc
http://myofasciite.fr/Contenu/Divers/201307_CAShaw_YLee_LTomljenovic.pdf
PRESENTATIONS
http://www.vaccinesafetyconference.com/presentation.html
Study RESOURCES - Dr Russell Blaylock
http://www.vaccinesafetyconference.com/resources.html
The Danger of Excessive Vaccination During Brain Development
The Case for a Link to Autism Spectrum Disorders
By Russell L. Blaylock, M.D.
http://articles.mercola.com/sites/articles/archive/2008/03/14/the-danger-of-excessive-vaccination-during-brain-development.aspx
Immune-Glutamatergic Dysfunction as a Central Mechanism of the Autism Spectrum Disorders
http://citeseerx.ist.psu.edu/viewdoc/download?doi=10.1.1.317.7642&rep=rep1&
http://www.utdallas.edu/~mxa049000/lessons/research/literature/Autism/new/Blaylock%20autism%20rev%20CMC%2009.pdf
Chronic Microglial Activation and Excitotoxicity Secondary to Excessive Immune Stimulation:
Possible Factors in Gulf War Syndrome and Autism
The Role of Excitotoxicity
Page 47. Damage to neuronal mechanisms is not limited to direct cytokine effects. The excitotoxicity initiated by microglial activation is even more important. In cases of HIV-1 dementia, it is known that brain quinolinic acid, an excitotoxin secreted by activated microglia, can increase more than 300-fold. In addition, glutamate is released in concentrations that are known to destroy neurons and/or synaptic connections.
Because glutamate can also activate microglia and enhance cytokine-induced neurodegeneration, a vicious cycle is created in which immune cytokines can stimulate release of glutamate, and glutamate in turn enhances cytokine production and release. Moreover, cytokines inhibit glutamate transporters, which play a critical role in removal of excess extracellular glutamate. Intimately linked to excitotoxicity is the generation of destructive free radicals, especially the reactive nitrogen species such as peroxynitrite and nitrosoperoxycarbonate. Much of the injury to dendrites, synapses and neurons, by both cytokines and excitotoxicity, is caused by free radicals.
The Role of Vaccines, page 49
Read more:
http://www.jpands.org/vol9no2/blaylock.pdf
Entropy 2012, 14(8), 1399-1442; doi:10.3390/e14081399
Review
The Initial Common Pathway of Inflammation, Disease, and Sudden Death
Robert M. Davidson 1,* and Stephanie Seneff
Abstract: In reviewing the literature pertaining to interfacial water, colloidal stability, and cell membrane function, we are led to propose that a cascade of events that begins with acute exogenous surfactant-induced interfacial water stress can explain the etiology of sudden death syndrome (SDS), as well as many other diseases associated with modern times. A systemic lowering of serum zeta potential mediated by exogenous cationic surfactant administration is the common underlying pathophysiology. The cascade leads to subsequent inflammation, serum sickness, thrombohemorrhagic phenomena, colloidal instability, and ultimately even death. We propose that a sufficient precondition for sudden death is lowered bioavailability of certain endogenous sterol sulfates, sulfated glycolipids, and sulfated glycosaminoglycans, which are essential in maintaining biological equipose, energy metabolism, membrane function, and thermodynamic stability in living organisms. Our literature review provides the basis for the presentation of a novel hypothesis as to the origin of endogenous bio-sulfates which involves energy transduction from sunlight. Our hypothesis is amply supported by a growing body of data showing that parenteral administration of substances that lower serum zeta potential results in kosmotropic cationic and/or chaotropic anionic interfacial water stress, and the resulting cascade.
http://www.mdpi.com/1099-4300/14/8/1399 (Also view full text from that link by clicking full study)
Warning to Pregnant Mothers - Toxic Dose of Aluminum in the Tdap, Pediatrician Paul Thomas (same video as at the top of page)
https://www.youtube.com/watch?v=VoY6vXEMsU8
Aluminum in Vaccines | A Pediatricians Warning To All Parents (same video as at the bottom of page)
https://www.youtube.com/watch?v=ee70I5bm3-k
The Initial Common Pathway of Inflammation, Disease, and Sudden Death, (full study source)
Pay particular attention to reading pages, Page 414-415 in regard to vaccine aluminum adjuvants, and as well pages 419-420 in regard to Gardasil.
Excerpted:
Page 414-415
The respiratory and auditory centers [218,219] in the brainstem are vulnerable to microvascular ischemic stress. So too is the pancreas [220–225]. Watershed and terminal vascular distributions are particularly susceptible to microvascular ischemic stress [223–225]. These vascular distributions would
be predicted to be highly susceptible to pathologic inflammatory stimulation and thrombohemorrhagic phenomena [3] induced by zeta potential-lowering and interfacial water stress-inducing properties of cationic kosmotropic electrolytes and polyelectrolyte surfactants. Dr Mohammed Al-Bayati’s
histopathologic analyses of SIDS [220–222] and so-called Shaken Baby Syndrome (SBS) victims [226] are most informative. Al-Bayati’s work provides strong support for the view that microvascular ischemia plays a central role in the pathophysiology of SIDS and, by inference, all SDS events [220–222]. Surfactant induced water stress [29,40,43,45,54,174,178,211,212] especially that associated with polycationic surfactants, is an important determinant of risk. Risk factors for SDS are synergistic and cumulative.
Expressed most simply, anything that perturbs the ZP toward less negative values and/or induces cationic kosmotropic or anionic chaotropic water stress represents a step in the direction of enzyme inhibition, protein dysfunction, cellular dysfunction, flocculation, gelation, coagulation,
microvascular ischemia, cellular anoxia, infarction, and death.
Transcytosis, both endocytosis and exocytosis, membrane potentials [219,227], and ion channels are all profoundly disrupted by polycationic surfactants [31,89,228–231]. A very relevant example is aluminum (Al3+), a kosmotropic trivalent cation, which is a potent and irreversible blocker of voltage activated calcium channels in mammalian neurons [31,228]. Ca-ATPase, protein kinase C and calmodulin (CaM) are biological systems known to be disrupted by aluminum [37,87,178,232]. Another very relevant example is mercury (Hg2+), a kosmotropic divalent cation. It has been shown in infant monkeys that the ethylmercury in thimerosal is more readily stored as inorganic mercury (Hg2+) in the brain than is orally-delivered ethylmercury and that inorganic mercury tends to linger longer in the tissues [231].
Thus, the sudden death syndrome can now be defined as an acute disruption of the colloidal stability of the vascular system, which triggers a cascade of events [97–100,229,230] leading to death, whenever compensatory mechanisms to maintain colloidal stability of the blood are insufficient. If compensatory mechanisms are sufficient, the cascade can instead lead to a new equilibrium. Mucopolysaccharides, also known as glycosaminoglycans (GAGs), contribute to the inflammatory state of the Shwartzman phenomenon [233–236]. Upon exposure to systemic stress, increases in sulfomucopolysaccharide incorporation occur throughout the body, and this is designated as the “universal nonspecific mesenchymal reaction” [3].
Gardasil
Page 419-420
2.9. Acute Shock and Role of Endothelial NOS-derived NO in SDS
Anaphylactic shock is a sudden, life-threatening allergic reaction associated with severe hypotension. Platelet-activating factor (PAF) is implicated in the cardiovascular dysfunctions occurring in various shock syndromes, including anaphylaxis. Anaphylactic shock is especially associated with quadrivalent HPV vaccine, which contains aluminum hydroxide. Based on the number of confirmed cases, the estimated rate of anaphylaxis following quadrivalent HPV vaccine was
significantly higher than identified in comparable school-based delivery of other vaccines [282].
In this review, we have described several of the adverse biophysical properties associated with cationic surfactants, Al3+ salts, and non-ionic surfactants. The U.S. CDC VAERS database provides considerable evidence of life threatening anaphylactic shock and anaphylactoid events associated with HPV vaccine, as well as with all of the aluminum (3+) containing vaccines, some of which resulted in sudden death. The U.S. CDC Vaccine Excipient & Media Summary states, “Excipients are inactive ingredients of a drug product necessary for production of a finished pharmaceutical formulation.” In the February 2012 update, the CDC disclosed that excipients in U.S. HPV vaccine include amorphous aluminum hydroxyphosphate sulfate, polysorbate 80, and sodium borate (from the manufacturer’s package insert of March, 2011). The relevance to SDS is apparent from reports of unexplained deaths of some women attributed to HPV vaccines in the CDC VAERS database, some of which were described variably as death during sleep or while bathing.
A reasonable question should be raised as to the purported safety and alleged biologic inactivity of the ingredients in the HPV vaccine, particularly aluminum, polysorbate 80, and sodium borate. Moreover, a further reasonable question should be Entropy 2012, 14 1420 raised as to the purported safety and alleged biologic inactivity of all of the aluminum and polysorbate 80 containing vaccines. This question may be further explored by analysis of the CDC VAERS database.
For example, CDC VAERS report ID: 337242 states “my daughter had her 3rd GARDASIL vaccine in Sept. She was a very healthy young lady, she went to take a shower and died. Autopsy report states undermined [undetermined] death. There was no sign of trauma to the body to indicate a fall. She had pointed the shower head away from her and she got down on her knees and put her head on the edge of the tub and passed away.”
Sources: http://www.mdpi.com/1099-4300/14/8/1399
http://people.csail.mit.edu/seneff/Entropy/Entropy1_downloaded.pdf
Stephanie Seneff
http://www.informatik.uni-trier.de/~ley/pers/hy/s/Seneff:Stephanie.html
Gardasil: New Study Brings More Safety Questions to Light
By Norma Erickson, President
Excerpts:
Why were HPV-16 L1 DNA fragments detected in post mortem samples taken six months after Gardasil vaccination and not the other vaccine-relevant types? Dr. Sin Hang Lee, of Milford Hospital and Milford Molecular Laboratory, may have provided an answer in his most recently published paper entitled, Topological conformational changes of human papillomavirus (HPV) DNA bound to an insoluble aluminum salt – A study by low temperature PCR.[1] His findings suggest that non-B-conformational changes in HPV L1 gene DNA fragments bound to the AAHS adjuvant may be genotype related, in other words specific to HPV-16.
In September 2011, SaneVax Inc. informed the FDA that despite all claims stating Gardasil contained ‘no viral DNA’ Dr. Lee had discovered there were indeed fragments of HPV-11, HPV-16 and HPV-18 L1 DNA firmly attached to Merck’s proprietary aluminum adjuvant in 100% of the samples he tested, but all were lacking a region amplifiable by an MY09 degenerate primer.[2] The FDA was quick to confirm that Gardasil does contain residual HPV L1 gene DNA fragments,[3] but that these fragments posed no health risk. The FDA completely ignored a request for further investigations put forth by the SaneVax Team.[4]
In light of the FDA statement corroborating Dr. Lee’s previous findings, the presence of HPV DNA fragments of vaccine origin in the bodies of recipients might be anticipated after intramuscular injections of Gardasil. However, finding HPV-16 L1 DNA fragments in post-mortem blood samples of a teenager who died six months after completion of 3 Gardasil injections without finding any other vaccine-relevant fragments was a surprise.[5] Obviously, further investigations were necessary.
At the request of SaneVax Inc., Dr. Lee agreed to use PCR amplification followed by direct DNA sequencing to try and determine what was going on. What he discovered is stated clearly in the conclusion of the above referenced paper. It says:
Where does this leave the average medical consumer? Unfortunately, it leaves them with the following unanswered questions:
Once injected, how long will the HPV-16 L1 DNA fragments attached to aluminum remain in my body?
Are the non-B conformation HPV fragments in Gardasil potentially harmful?
Will the non-B conformation DNA fragments in Gardasil induce autoimmune disorders?
Will the non-B conformation DNA get integrated in the genome causing mutagenesis and/or cancer?
The scientific community needs to investigate these potential risks immediately. Medical consumers need to know the risks as well as any potential benefits before they decide if Gardasil is right for them.
In the interest of public health and safety, the FDA needs to rescind approval for Gardasil until satisfactory answers are provided to the four questions above. The time for poke and hope is long since passed. Medical consumers need proof this vaccine is safe.
Read more:
http://sanevax.org/gardasil-new-study-brings-more-safety-questions-to-light/
Death after Quadrivalent Human Papillomavirus (HPV) Vaccination: Causal or Coincidental?
Conclusions: Our study suggests that HPV vaccines containing HPV-16L1 antigens pose an inherent risk for
triggering potentially fatal autoimmune vasculopathies.
http://www.rescuepost.com/files/ltshaw-death-after-quadrivalent-hpv-vaccination-pharma-reg-affairs-2012.pdf
The Potential Significance of Aluminum/DNA Compounds in Gardasil on Health
http://sanevax.org/the-potential-significance-of-aluminumdna-compounds-in-gardasil-on-health/
The persistence of HPV DNA fragments and adverse effects in HPV shot recipients
http://www.examiner.com/article/the-persistence-of-hpv-dna-fragments-and-adverse-effects-hpv-shot-recipients
Gardasil: Are you paying for your own bullet?
The temperature of the heated controversy concerning Gardasil was recently raised even more when Dr. Bernhard Dalbergue (France), former pharmaceutical industry physician with Merck, recently predicted that the vaccine will become the greatest medical scandal of all times.
In an interview in the April 2014 issue (no. 66) of the magazine Principes de Santé (Health Principles), Dr. Dalbergue, who has worked for over twenty years with the industry, describes the widespread corruption and his concern that the health of patients is sacrificed on the altar of profitability.
Dr. Dalbergue stated:
I predict that Gardasil will become the greatest medical scandal of all times because at some point in time, the evidence will add up to prove that this vaccine has absolutely no effect on cervical cancer and that all the very many adverse effects which destroy lives and even kill, serve no other purpose than to generate profit for the manufacturers.
According to Dr. Dalbergue the pharmaceutical industry has hardened considerably during the last decade, as shown by increased violations of ethics, manipulation of clinical trial data, widespread corruption, gross conflicts of interest and generally less emphasis on pharmacovigilance.
Read more:
http://sanevax.org/gardasil-paying-for-your-own-bullet/
Why is neurotoxic aluminum in vaccines, (Over 600 mcg in all three shots of Gardasil. The brand name Cervarix now showing equally as harmful, with its new APo4 adjuvant). http://en.wikipedia.org/wiki/Cervarix
Excerpt:
Aluminum hydroxide is a neurotoxic poison
This form of aluminum is a protoplasmic poison and a potent neurotoxin that is completely unnatural to the biochemical process of any life form on earth. The American Academy of Pediatrics has stated that aluminum is now being implicated as interfering with a variety of cellular and metabolic processes in the nervous system and other tissues. Aluminum toxicity is known to cause encepthalitis, bone disease and anemia.
“Aluminum hydroxide is used in vaccines to increase the body’s production of antibodies, though no one knows how it works,” says Purdue researcher Stanley Hem, professor of industrial and physical pharmacy.
Antigens are protein molecules that stimulate the immune system. Antibodies are protein molecules made by the immune system to defend against foreign substances. In the 1930’s, vaccine researchers tested a number of ingredients to see what would effectively bring antigens into the body so the immune system of the individual would produce antibodies.
Aluminum was proved to be an effective adjuvant or substance that irritates the immune system and causes antibody production.
Read more:
http://www.naturalhealth365.com/vaccine_dangers/toxic_aluminum.html
Gardasil-The Real Truth
http://www.vacfacts.info/gardasil---the-real-truth.html
09 Andrew Moulden En 07 de 11
http://www.youtube.com/watch?v=8hUOVChsJ9w
09 Andrew Moulden En 06 de 11
http://www.youtube.com/watch?v=58KLLm1q0_Y
Vaccination toxicity: The Zeta phase of MASS and “blood sludging”
http://www.vacfacts.info/vaccination-toxicity-the-zeta-phase-of-mass-and-ldquoblood-sludgingrdquo.html
TOXICOLOGICAL PROFILE FOR ALUMINUM
http://www.atsdr.cdc.gov/ToxProfiles/tp22.pdf
----------------
Crit Rev Toxicol. 2014 Oct;44 Suppl 4:1-80. doi: 10.3109/10408444.2014.934439.
Systematic review of potential health risks posed by pharmaceutical, occupational and consumer exposures to metallic and nanoscale aluminum, aluminumoxides, aluminum hydroxide and its soluble salts.
Willhite CC1, Karyakina NA, Yokel RA, Yenugadhati N, Wisniewski TM, Arnold IM, Momoli F, Krewski D.
Abstract
Abstract Aluminum (Al) is a ubiquitous substance encountered both naturally (as the third most abundant element) and intentionally (used in water, foods, pharmaceuticals, and vaccines); it is also present in ambient and occupational airborne particulates. Existing data underscore the importance of Al physical and chemical forms in relation to its uptake, accumulation, and systemic bioavailability. The present review represents a systematic examination of the peer-reviewed literature on the adverse health effects of Al materials published since a previous critical evaluation compiled by Krewski et al. (2007) . Challenges encountered in carrying out the present review reflected the experimental use of different physical and chemical Al forms, different routes of administration, and different target organs in relation to the magnitude, frequency, and duration of exposure. Wide variations in diet can result in Al intakes that are often higher than the World Health Organization provisional tolerable weekly intake (PTWI), which is based on studies with Al citrate. Comparing daily dietary Al exposures on the basis of "total Al"assumes that gastrointestinal bioavailability for all dietary Al forms is equivalent to that for Al citrate, an approach that requires validation. Current occupational exposure limits (OELs) for identical Al substances vary as much as 15-fold. The toxicity of different Al forms depends in large measure on their physical behavior and relative solubility in water. The toxicity of soluble Al forms depends upon the delivered dose of Al(+3) to target tissues. Trivalent Al reacts with water to produce bidentate superoxide coordination spheres [Al(O2)(H2O4)(+2) and Al(H2O)6 (+3)] that after complexation with O2(•-), generate Al superoxides [Al(O2(•))](H2O5)](+2). Semireduced AlO2(•) radicals deplete mitochondrial Fe and promote generation of H2O2, O2 (•-) and OH(•). Thus, it is the Al(+3)-induced formation of oxygen radicals that accounts for the oxidative damage that leads to intrinsic apoptosis. In contrast, the toxicity of the insoluble Al oxides depends primarily on their behavior as particulates. Aluminum has been held responsible for human morbidity and mortality, but there is no consistent and convincing evidence to associate the Al found in food and drinking water at the doses and chemical forms presently consumed by people living in North America and Western Europe with increased risk for Alzheimer's disease (AD). Neither is there clear evidence to show use of Al-containing underarm antiperspirants or cosmetics increases the risk of AD or breast cancer. Metallic Al, its oxides, and common Al salts have not been shown to be either genotoxic or carcinogenic. Aluminum exposures during neonatal and pediatric parenteral nutrition (PN) can impair bone mineralization and delay neurological development. Adverse effects to vaccines with Al adjuvants have occurred; however, recent controlled trials found that the immunologic response to certain vaccines with Al adjuvants was no greater, and in some cases less than, that after identical vaccination without Al adjuvants. The scientific literature on the adverse health effects of Al is extensive. Health risk assessments for Al must take into account individual co-factors (e.g., age, renal function, diet, gastric pH). Conclusions from the current review point to the need for refinement of the PTWI, reduction of Al contamination in PN solutions, justification for routine addition of Al to vaccines, and harmonization of OELs for Al substances.
http://www.ncbi.nlm.nih.gov/pubmed/25233067
Immunotherapy. 2014;6(10):1055-71. doi: 10.2217/imt.14.81.
Are there negative CNS impacts of aluminum adjuvants used in vaccines and immunotherapy?
Shaw CA1, Li D, Tomljenovic L.
Abstract
In spite of a common view that aluminum (Al) salts are inert and therefore harmless as vaccine adjuvants or in immunotherapy, the reality is quite different. In the following article we briefly review the literature on Al neurotoxicity and the use of Al salts as vaccine adjuvants and consider not only direct toxic actions on the nervous system, but also the potential impact for triggering autoimmunity. Autoimmune and inflammatory responses affecting the CNS appear to underlie some forms of neurological disease, including developmental disorders. Al has been demonstrated to impact the CNS at every level, including by changing gene expression. These outcomes should raise concerns about the increasing use of Al salts as vaccine adjuvants and for the application as more general immune stimulants.
http://www.ncbi.nlm.nih.gov/pubmed/25428645
Biotech Histochem. 2015 Feb;90(2):132-9. doi: 10.3109/10520295.2014.965277. Epub 2014 Oct 14.
A histological study of toxic effects of aluminium sulfate on rat hippocampus.
Çabuş N1, Oğuz EO, Tufan AÇ, Adıgüzel E.
Abstract
Aluminium has toxic effects on many organ systems of the human body. Aluminium toxicity also is a factor in many neurodegenerative diseases. We investigated changes in numbers of hippocampal neurons in rats exposed to aluminium using an optical fractionator and we investigated aluminium-induced apoptosis using the transferase mediated dUTP nick end labeling (TUNEL) assay. Twenty-four female rats were divided equally into control, sham and aluminium-exposed groups. The control group received no treatment. The two treatment groups were injected intraperitoneally with 1 ml 0.9% saline without (sham) and with 3 mg/ml aluminium sulfate every day for two weeks. Following the treatments, the brains were removed, the left hemisphere was used for hippocampal neuron counting using an optical fractionator and the right hemisphere was investigated using hippocampal TUNEL assay to determine the apoptotic index. The number of neurons in the stratum pyramidale of the hippocampus was significantly less in the aluminium group than in the control and sham groups; there was no significant difference between the control and sham groups. The apoptotic index also was significantly higher in the aluminium group than in the other two groups. We quantified the toxic effects of aluminium on the rat hippocampus and determined that apoptosis was the mechanism of aluminium-induced neuron death in the hippocampus.
http://www.ncbi.nlm.nih.gov/pubmed/25314162
Int J Alzheimers Dis. 2011 Mar 8;2011:276393. doi: 10.4061/2011/276393.
Link between Aluminum and the Pathogenesis of Alzheimer's Disease: The Integration of the Aluminum and Amyloid Cascade Hypotheses.
Kawahara M1, Kato-Negishi M.
Abstract
Whilst being environmentally abundant, aluminum is not essential for life. On the contrary, aluminum is a widely recognized neurotoxin that inhibits more than 200 biologically important functions and causes various adverse effects in plants, animals, and humans. The relationship between aluminum exposure and neurodegenerative diseases, including dialysis encephalopathy, amyotrophic lateral sclerosis and Parkinsonism dementia in the Kii Peninsula and Guam, and Alzheimer's disease (AD) has been suggested. In particular, the link between aluminum and Alzheimer's disease has been the subject of scientific debate for several decades. However, the complex characteristics of aluminum bioavailability make it difficult to evaluate its toxicity and therefore, the relationship remains to be established. Mounting evidence has suggested that significance of oligomerization of β-amyloid protein and neurotoxicity in the molecular mechanism of AD pathogenesis. Aluminum may play crucial roles as a cross-linker in β-amyloid oligomerization. Here, we review the detailed characteristics of aluminum neurotoxicity based on our own studies and the recent literatures. Our aim is to revisit the link between aluminum and AD and to integrate aluminum and amyloid cascade hypotheses in the context of β-amyloid oligomerization and the interactions with other metals.
http://www.ncbi.nlm.nih.gov/pubmed/21423554
J Trace Elem Med Biol. 2012 Oct;26(4):291-3. doi: 10.1016/j.jtemb.2012.02.005. Epub 2012 Mar 15.
Aluminium overload after 5 years in skin biopsy following post-vaccination with subcutaneous pseudolymphoma.
Guillard O1, Fauconneau B, Pineau A, Marrauld A, Bellocq JP, Chenard MP.
Abstract
Aluminium hydroxide is used as an effective adjuvant in a wide range of vaccines for enhancing immune response to the antigen. The pathogenic role of aluminium hydroxide is now recognized by the presence of chronic fatigue syndrome, macrophagic myofasciitis and subcutaneous pseudolymphoma, linked to intramuscular injection of aluminium hydroxide-containing vaccines. The aim of this study is to verify if the subcutaneous pseudolymphoma observed in this patient in the site of vaccine injection is linked to an aluminium overload. Many years after vaccination, a subcutaneous nodule was discovered in a 45-year-old woman with subcutaneous pseudolymphoma. In skin biopsy at the injection site for vaccines, aluminium (Al) deposits are assessed by Morin stain and quantification of Al is performed by Zeeman Electrothermal Atomic Absorption Spectrophotometry. Morin stain shows Al deposits in the macrophages, and Al assays (in μg/g, dry weight) were 768.10±18 for the patient compared with the two control patients, 5.61±0.59 and 9.13±0.057. Given the pathology of this patient and the high Al concentration in skin biopsy, the authors wish to draw attention when using the Al salts known to be particularly effective asadjuvants in single or repeated vaccinations. The possible release of Al may induce other pathologies ascribed to the well-known toxicity of this metal.
http://www.ncbi.nlm.nih.gov/pubmed/22425036
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Etiology: An Editorial on the Prevention of Communication Disorders
Excerpt: In the field of communication disorders, perhaps the most neglected area in the scope of practice of speech-language pathologists and audiologists is prevention [5]. Yet to prevent disorders it is necessary first and foremost to seek out their causes. Let this editorial serve as a call for papers seeking out causes with a view toward prevention. The work can be guided in part, at least, by the sure knowledge that all disorders, disease conditions, and even death itself involve breakdowns in the biological control systems that enable health and well-being. Understanding the disruptive factors that cause such breakdowns [6] will go a long way toward enabling their prevention. Also we know now for a certainty that certain environmental toxins are causally involved [7].
http://www.esciencecentral.org/journals/etiology-an-editorial-on-the-prevention-of-communication-disorders-JCDSHA.e101.php?aid=15245
Michigan doctor reveals plan to stop autism
April is National Autism Awareness Month and the Centers for Disease Control (CDC) now estimates that one in 68 children has been identified with autism spectrum disorder (ASD). The rates have increased 30% since the reported estimate of one in 88 two years ago. The rate was one in 10,000 in 1970.
A physician, Dr. Marvin Anderson, has been treating children with ASD in his clinic at Abba’s Place since 2009. He has written a book entitled Autism Prevention, Care and Management. In his book, Dr. Anderson describes his experiences helping children with autism and attention deficit hyperactivity disorder (ADHD) and he proposes a positive and hopeful solution to ending the autism epidemic that is spreading throughout the world. His treatment for ASD and ADHD is primarily directed to the digestive tract, including the liver. Animal studies have shown an intriguing connection between inflammation in the intestinal tract and inflammation in the brain. Autism also can involve impairments in the body’s detoxification pathways. Dr. Anderson’s program includes identifying contaminants that are present in his patients and creating a detoxification plan for their safe and efficient removal. Inflammation elsewhere in the body, including the brain, is also addressed. An important part of this plan involves care of the liver using the principles of liver cleansing advanced by Dr. Sandra Cabot in her best-selling book, The Liver Cleansing Diet.
Dr. Anderson has discussed his plan for ending the autism epidemic in detail with state of Michigan Representative Ray Franz. The plan consists of enacting three laws by the state legislature.
I. Require that all newborn infants receive an autism prevention screening test prior to receiving any vaccinations. The “one size fits all” approach to vaccinations is no longer working. According to Dr. Gregory Poland et al. in Vaccinomics and Personalized Vaccinology, included in the 2012 Jordan Report, Accelerated development of vaccines, “...significant individual variation exists in risk of adverse events and in immune response to a given vaccine.
Read more:
http://www.examiner.com/article/michigan-doctor-reveals-plan-to-stop-autism
THE BOOK: Autism Prevention Care and Management
Written by a physician with 10 year’s experience caring for children with this calamity – summarizes the problem and solution to the epidemic of autism that is spreading throughout the world.
http://www.autismatabbasplace.com/book.html
Phenotypic expression of autoimmune autistic disorder (AAD): A major subset of autism
Vijendra K. Singh, PhD
Brain State International Research Center, Scottsdale, AZ, USA
BACKGROUND: Autism causes incapacitating neurologic problems in children that last a lifetime. The author of this article previously hypothesized that autism may be caused by autoimmunity to the brain, possibly triggered by a viral infection. This article is a summary of laboratory findings to date plus new data in support of an autoimmune pathogenesis for autism.
METHODS: Autoimmune markers were analyzed in the sera of autistic and normal children, but the cerebrospinal fluid (CSF) of some autistic children was also analyzed. Laboratory procedures included enzyme-linked immunosorbent assay and protein immunoblotting assay.
RESULTS: Autoimmunity was demonstrated by the presence of brain autoantibodies, abnormal viral serology, brain and viral antibodies in CSF, a positive correlation between brain autoantibodies and viral serology, elevated levels of proinflammatory cytokines and acute-phase reactants, and a positive response to immunotherapy. Many autistic children harbored brain myelin basic protein autoantibodies and elevated levels of antibodies to measles virus and measles-mumps-rubella (MMR) vaccine. Measles might be etiologically linked to autism because measles and MMR antibodies (a viral marker) correlated positively to brain autoantibodies (an autoimmune marker)—salient features that characterize autoimmune pathology in autism. Autistic children also showed elevated levels of acute-phase reactants—a marker of systemic inflammation.
CONCLUSION: The scientific evidence is quite credible for our autoimmune hypothesis, leading to the identification of autoimmune autistic disorder (AAD) as a major subset of autism. AAD can be identified by immune tests to determine immune problems before administering immunotherapy. The author has advanced a speculative neuroautoimmune (NAI) model for autism, in which virus-induced autoimmunity is a key player. The latter should be targeted by immunotherapy to help children with autism.
https://www.aacp.com/Pages.asp?AID=7937
Is Encephalopathy a Mechanism to Renew Sulfate in Autism?
Stephanie Seneff 1,*, Ann Lauritzen 2 , Robert M. Davidson 3 and Laurie Lentz-Marino 4
Entropy; Jan2013, Vol. 15 Issue 1, p372
ABSTRACT This paper makes two claims: (1) autism can be characterized as a chronic lowgrade encephalopathy, associated with excess exposure to nitric oxide, ammonia and glutamate in the central nervous system, which leads to hippocampal pathologies and resulting cognitive impairment, and (2), encephalitis is provoked by a systemic deficiency in sulfate, but associated seizures and fever support sulfate restoration. We argue that impaired synthesis of cholesterol sulfate in the skin and red blood cells, catalyzed by sunlight and nitric oxide synthase enzymes, creates a state of colloidal instability in the blood manifested as a low zeta potential and increased interfacial stress. Encephalitis, while life-threatening, can result in partial renewal of sulfate supply, promoting neuronal survival. Research is cited showing how taurine may not only help protect neurons from hypochlorite exposure, but also provide a source for sulfate renewal. Several environmental factors can synergistically promote the encephalopathy of autism, including the herbicide, glyphosate, aluminum, mercury, lead, nutritional deficiencies in thiamine and zinc, and yeast overgrowth due to excess dietary sugar. Given these facts, dietary and lifestyle changes, including increased sulfur ingestion, organic whole foods, increased sun exposure, and avoidance of toxins such as aluminum, mercury, and lead, may help to alleviate symptoms or, in some instances, to prevent autism altogether.
http://www.mdpi.com/1099-4300/15/1/372
Autism: A neuroepigenetic disorder, By Richard C. Deth, PhD
http://www.autismone.org/sites/default/files/Deth_ASD03.pdf
Empirical Data Confirm Autism Symptoms Related to Aluminum and Acetaminophen Exposure
Stephanie Seneff, Robert M. Davidson, and Jingjing Liu
http://www.mdpi.com/1099-4300/14/11/2227
http://people.csail.mit.edu/seneff/Entropy/entropy-14-02227.pdf
GLUTATHIONE Scientific Research
Our findings suggest that acetaminophen administration selectively depletes (within 2 hr) mitochondrial glutathione, and produces local toxicity by altering membrane permeability and decreasing the efficiency of oxidative phosphorylation. This renders mitochondria more susceptible to oxidative damage… PMID: 8937421
http://www.readisorb.com/science/glutathione_scientific_researc.html
Biochem Pharmacol. 1996 Oct 25;52(8):1147-54.
Effect of acetaminophen administration on hepatic glutathione compartmentation and mitochondrial energy metabolism in the rat.
http://www.ncbi.nlm.nih.gov/pubmed/8937421
Scientific Research, 2nd Page
http://www.readisorb.com/science/
Tim Guilford, MD
Glutathione in Health and Disease
http://www.svhi.com/newsletters/2005/slf-122005.pdf
Glutathione
http://www.readisorb.com/
Glutathione, Tylenol, Vaccine Adverse Reactions, and ASD
http://www.vacfacts.info/glutathione-tylenol-vaccine-adverse-reactions-and-asd.html
Neurodegenerative Diseases: Neurotoxins as Sufficient Etiologic Agents?
Christopher A. Shaw and Günter U. Höglinger
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2814816/
Neuroscience and Biobehavioral Reviews
Analysis of neurological disease in four dimensions: insight from ALS-PDC epidemiology and animal models
The causal factor(s) responsible for sporadic neurological diseases are unknown and the stages of disease progression remain undefined and poorly understood. We have developed an animal model of amyotrophic lateral sclerosis-parkinsonism dementia complex which mimics all the essential features of the disease with the initial neurological insult arising from neurotoxins contained in washed cycad seeds. Animals fed washed cycad develop deficits in motor, cognitive, and sensory behaviors that correlate with the loss of neurons in specific regions of the central nervous system. The ability to recreate the disease by exposure to cycad allows us to extend the model in multiple dimensions by analyzing behavioral, cellular, and biochemical changes over time. In addition, the ability to induce toxin-based neurodegeneration allows us to probe the interactions between genetic and epigenetic factors. Our results show that the impact of both genetic causal and susceptibility factors with the cycad neurotoxins are complex. The article describes the features of the model and suggests ways that our understanding of cycad-induced neurodegeneration can be used to decipher and identify the early events in various human neurological diseases.
http://yadda.icm.edu.pl/yadda/element/bwmeta1.element.elsevier-a4f127e4-0c75-3f6d-bb32-9406a3136a76
And to realize that in any of the studies that the CDC has considered as to vaccine toxicity, none of that has been studied, and nor as well has any basic physiological science like this been addressed nor even acknowledged. They are yet by CHOICE, in the dark ages, as to their known and accepted knowledge, and of the human body, and its immune system
Dr Blaylock, a Board-certified neurosurgeon, Visiting Professor of Biology at Belhaven College, Jackson, Mississippi, and member of the Editorial Board of the Journal of the American Nutraceutical Association (JANA), is the author of three books on excitotoxicity: Excitoxicity: the taste that kills, Health and nutrition secrets, and Natural strategies for cancer patients.
EXCITOTOXICITY: A POSSIBLE CENTRAL MECHANISM IN FLUORIDE NEUROTOXICITY, (the fluoride and aluminum connection)
by Russell L Blaylocka, Ridgeland, MS, USA
SUMMARY: Recent evidence indicates that fluoride produces neuronal destruction and synaptic injury by a mechanism that involves free radical production and lipid peroxidation. For a number of pathological disorders of the central nervous system (CNS), excitotoxicity plays a critical role. Various studies have shown that many of the neurotoxic metals, such as mercury, lead, aluminum, and iron also injure neural elements in the CNS by an excitotoxic mechanism. Free radical generation and lipid peroxidation, especially in the face of hypomagnesemia and low neuronal energy production, also magnify excitotoxic sensitivity of neurons and their elements. This paper reviews briefly some of the studies that point to a common mechanism for the CNS neurotoxic effects of fluoride and calls for research directed toward further elucidation of this mechanism.
http://www.fluorideresearch.org/374/files/374301-314.pdf
Dr Andrew Wakefield Defends His Research, (a quite lengthy video, but puts the TRUTH front and center, all of it).
https://www.youtube.com/watch?v=i6DuBR_xGQg
Vaccine Safety Conference Session 15 Dr. Andrew Wakefield
http://www.youtube.com/watch?v=8Ei0QSvKdgw
http://www.vaccinesafetyconference.com/videos.html#WakefieldVideo
Selective Hearing: Brian Deer and the GMC
http://topdocumentaryfilms.com/selective-hearing-brian-deer-and-the-gmc/
Research References, (endless, and all of it is ignored by the CDC)
http://www.callous-disregard.com/research.htm
Dr Andrew Wakefield - MMR Vaccine - Truth and Reality
http://www.vacfacts.info/dr-andrew-wakefield---mmr-vaccine---truth-and-reality.html
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Journal of the Neurological Sciences
Volume 280, Issues 1–2, 15 May 2009, Pages 101–108
Biomarkers of environmental toxicity and susceptibility in autism
Abstract
Autism spectrum disorders (ASDs) may result from a combination of genetic/biochemical susceptibilities in the form of a reduced ability to excrete mercury and/or increased environmental exposure at key developmental times. Urinary porphyrins and transsulfuration metabolites in participants diagnosed with an ASD were examined. A prospective, blinded study was undertaken to evaluate a cohort of 28 participants with an ASD diagnosis for Childhood Autism Rating Scale (CARS) scores, urinary porphyrins, and transsulfuration metabolites. Testing was conducted using Vitamin Diagnostics, Inc. (CLIA-approved) and Laboratoire Philippe Auguste (ISO-approved). Participants with severe ASDs had significantly increased mercury intoxication-associated urinary porphyrins (pentacarboxyporphyrin, precoproporphyrin, and coproporphyrin) in comparison to participants with mild ASDs, whereas other urinary porphyrins were similar in both groups. Significantly decreased plasma levels of reduced glutathione (GSH), cysteine, and sulfate were observed among study participants relative to controls. In contrast, study participants had significantly increased plasma oxidized glutathione (GSSG) relative to controls. Mercury intoxication-associated urinary porphyrins were significantly correlated with increasing CARS scores and GSSG levels, whereas other urinary porphyrins did not show these relationships. The urinary porphyrin and CARS score correlations observed among study participants suggest that mercury intoxication is significantly associated with autistic symptoms. The transsulfuration abnormalities observed among study participants indicate that mercury intoxication was associated with increased oxidative stress and decreased detoxification capacity.
http://www.sciencedirect.com/science/article/pii/S0022510X08004310
Mitochondrial Dysfunction in Autism
Context Impaired mitochondrial function may influence processes highly dependent on energy, such as neurodevelopment, and contribute to autism. No studies have evaluated mitochondrial dysfunction and mitochondrial DNA (mtDNA) abnormalities in a well-defined population of children with autism.
Main Outcome Measures Oxidative phosphorylation capacity, mtDNA copy number and deletions, mitochondrial rate of hydrogen peroxide production, and plasma lactate and pyruvate.
Conclusion In this exploratory study, children with autism were more likely to have mitochondrial dysfunction, mtDNA overreplication, and mtDNA deletions than typically developing children.
Autism spectrum disorders (ASD) are characterized by impaired social interaction, problems with verbal and nonverbal communication, and repetitive or severely restricted activities and interests.1 Limited scientific advances have been made regarding the causes of autism, with general agreement that both genetic and environmental factors contribute to this disorder.
Some reports have suggested that mitochondrial dysfunction and altered energy metabolism may influence the social and cognitive deficits in autism2- 4; however, most reports involved only 1 or a few isolated cases.2,5 A school-based study of 69 children aged 10 to 14 years with confirmed autism or ASD found mitochondrial respiratory chain dysfunction in 7.2%.4 Considering the limitations of elevated lactate-to-pyruvate ratios and the bias toward skeletal muscle disturbances in the study sample, some cases were likely overlooked, and the incidence in the affected population could actually be higher than reported. To our knowledge, there are no systematic studies aimed at investigating changes in mitochondrial function, mitochondrial DNA (mtDNA) copy number, mtDNA deletions, and oxidative stress in children with autism who have been clinically well defined.
Mitochondrial function in disease often has been investigated in muscle biopsies6; however, the detection of mitochondrial defects in readily available cells from body fluids (lymphocytes and platelets7) would be valuable under the assumption that many such defects may not be confined to muscle or the brain, tissues in which mitochondrial diseases are most strongly evident. Considering that the energy requirement for lymphocytes is derived almost equally from glycolysis and oxidative phosphorylation,8 we tested the hypothesis that children with full syndrome autism have dysfunctional mitochondria in peripheral blood lymphocytes.
Objective To evaluate mitochondrial defects in children with autism.
Read more:
http://jama.ama-assn.org/content/304/21/2389.abstract
Unvaccinated Children Will Be Healthiest Among Future Generations Studies and Surveys Predict
http://www.fhfn.org/unvaccinated-children-will-be-healthiest-among-future-generations-studies-and-surveys-predict/
Vaccine Truth Informational Brochures:
Do not allow all of the vaccine-injured childrens injuries to be in vain. Educate others in honor of them. Be the Voice for those who don't have one. Do not be silent. You can inform other parents. We provide multiple free brochures you can give to educate other parents.
Download and print them now.
http://www.educate4theinjured.org/eric/4571993523
Educate Others: (Three brochures)
http://www.educate4theinjured.org/eric/4571993523#!brochures/cee5
CURRENT VACCINE SCHEDULE- 26 DOSES BEFORE THE 1ST YEAR OF LIFE. 49 DOSES BY AGE 6. Do you have your 49 doses? Nope, NEITHER DO I, OR HER OR HIM. Look around you. Who has had the 49 doses we give our children? OUR CHILDHOOD VACCINES HAVE ALREADY WANED! SINCE AROUND 90% OF ADULTS ARE CONSIDERED UNVACCINATED, WHY ARENT WE HAVING EPIDEMICS? Are so many vaccines safe?
Is Aborted Fetal DNA in Vaccines Linked to Autism?
The vaccine-autism connection was first hypothesized following the introduction of a new measles, mumps and rubella (MMR) vaccine to the U.S. in 1979, with complete U.S. market share by 1983, and to the UK in 1988. Autism rates began to rise in the U.S. after 1979 and rose dramatically after 1983, and likewise rose in the UK after 1988, leading physicians to suspect a link. Initially, the measles component of this vaccine, MMR II, was suspected to be the culprit. Subsequent studies have also focused on the presence of mercury in vaccines, which incidentally, the MMR II vaccine did not contain.
Those studies have largely ruled out the new measles portion of the MMR II or mercury as the environmental trigger for autism. However, the compelling temporal association between this new MMR vaccine and autism cannot be ignored or explained away. What has been ignored is the fact that this new MMR vaccine introduced the use of aborted fetal cells for vaccine production. At one point, as much as 94 percent of children in the U.S. and 98 percent of children in the UK were given this vaccine.
Today, more than 23 vaccines are contaminated by the use of aborted fetal cells. There is no law that requires that consumers be informed that some vaccines are made using aborted fetal cells and contain residual aborted fetal DNA. While newer vaccines produced using aborted fetal cells do inform consumers, in their package inserts, that the vaccines contain contaminating DNA from the cell used to produce the vaccine, they do not identify the cells as being derived from electively aborted human fetuses.
In other words, they tell you what is in the vaccine, but they don’t fully inform you where it came from. The earliest aborted fetal cell-produced vaccines such as Meruvax (rubella) and MMR II do not even inform consumers that the vaccines contain contaminating DNA from the cell used to produce them. Furthermore, it is unconscionable that the public-health risk of injecting our children with residual contaminating human aborted fetal DNA has been ignored.
How could the contaminating aborted fetal DNA create problems? It creates the potential for autoimmune responses and/or inappropriate insertion into our own genomes through a process called recombination. There are groups researching the potential link between this DNA and autoimmune diseases such as juvenile (type I) diabetes, multiple sclerosis and lupus. Our organization, [3] Sound Choice Pharmaceutical Institute (SCPI), is focused on studying the quantity, characteristics and genomic recombination of the aborted fetal DNA found in many of our vaccines.
Read more: http://www.physiciansforlife.org/content/view/1758/2/
http://media.wix.com/ugd/c2b39a_6c6beca3ffbb4c249b3bb66cb55eb307.pdf
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“Aluminum is an experimentally demonstrated neurotoxin and the most commonly used vaccine adjuvant. Despite almost 90 years of widespread use of aluminum adjuvants, medical science's understanding about their mechanisms of action is still remarkably poor. There is also a concerning scarcity of data on toxicology and pharmacokinetics of these compounds. In spite of this, the notion that aluminum in vaccines is safe appears to be widely accepted.
Experimental research, however, clearly shows that aluminum adjuvants have a potential to induce serious
immunological disorders in humans. In particular, aluminum in adjuvant form carries a risk for autoimmunity, long-term brain inflammation and associated neurological complications and may thus have profound and widespread adverse health consequences. In our opinion, the possibility that vaccine benefits may have been overrated and the risk of potential adverse effects underestimated, has not been rigorously evaluated in the medical and scientific community”
Aluminum vaccine adjuvants: are they safe? [Curr Med Chem. 2011] - PubMed - NCBI
http://www.ncbi.nlm.nih.gov/pubmed/21568886
BE AWARE OF THE DELAYED REACTION!
HOW LONG AFTER A VACCINE DO INJURIES OCCUR?
IMMEDIATELY TO YEARS LATER.
OFTEN 13-19 DAYS AFTER VACCINATION.
YOU KNOW THE SCREAMS
Arched back. Inconsolable crying. ENCEPHALITIS. BRAIN DAMAGE. Many parents do not recognize the link between
vaccination and reaction or injury because often times the reaction is delayed until after the vaccine virus incubates. Almost a month after they get their shots. This takes up to and around 3-4 weeks after the child is injected to occur. WATCH YOUR BABY AROUND THE 2ND-3RD WEEK! KEEP THEM CLOSE TO YOU! COMFORT THEM IF THEY BECOME SICK. NO TYLENOL OR ADVIL. THIS HURTS THE DETOXIFICATION PROCESS AND PUTS YOUR BABY AT GREATER RISK FOR SEIZURES.
"There is insufficient evidence to support routine vaccination of healthy persons of any age. - Paul Frame, M.D., Journal of Family Practice"
"My suspicion, which is shared by others in my profession, is that the nearly 10,000 SIDS deaths that occur in the United States each year are related to one or more of the vaccines that are routinely given children. The pertussis vaccine is the most likely villain, but it could also be one or more of the others." --Dr.
Mendelsohn, M.D.
"The evidence for indicting immunizations for SIDS is circumstantial, but compelling. However, the keepers of the keys to medical-research funds are not interested in researching this very important lead to the cause of an ongoing, and possibly preventable, tragedy. Anything that implies that immunizations are not the greatest medical advance in the history of public health is ignored or ridiculed. Can you imagine the economic and political import of discovering that immunizations are killing thousands of babies?" --Dr. Douglass M.D.
Crib death was so infrequent in the prevaccine era that it was not even mentioned in the statistics, but it started to climb in the 1950s with the spread of mass vaccination against diseases of childhood. --
Harris L.Coulter, PhD."
Read more:
http://media.wix.com/ugd/c2b39a_03f8aac260f54057bd33359c4ec6c03c.pdf
Memorial to Victims of the Silent War ~ VACCINES ~
Cease for Peace! ~ Interviews with Sallie O. Elkordy
http://billiontoddlermarchforsurvival.blogspot.com/
5 Reasons Not To Get The Flu Shot:
http://vaccineresistancemovement.org/?p=12642
VRM: The Problem With Vaccines Part 4 – Primary Aspects of Vaccine Toxicity Affecting The Body
http://vaccineresistancemovement.org/?p=8787
--------------
Review of Vaccine Induced Immune Overload and the Resulting Epidemics of
Type 1 Diabetes and Metabolic Syndrome, Emphasis on Explaining the Recent
Accelerations in the Risk of Prediabetes and other Immune Mediated Diseases
J Barthelow Classen MD
3637 Rockdale Road, Manchester, MD 21102, USA
Abstract
There has been an epidemic of inflammatory diseases that has paralleled the epidemic on iatrogenic immune stimulation with vaccines. Extensive evidence links vaccine induced immune over load with the epidemic of type 1 diabetes. More recent data indicates that obesity, type 2 diabetes and other components of metabolic syndrome are highly associated with immunization and may be manifestations of the negative feedback loop of the immune system
reacting to the immune overload. The epidemic of diabetes/prediabetes appears to be accelerating at a time when the prevalence of obesity has stabilized, indicating that the negative feedback system of the immune system has been over whelmed. The theory of vaccine induced immune overload can explain the key observations that have confounded many competing hypothesis. The current paper reviews the evidence that vaccine induced immune overload explains the disconnect between the increase in prediabetes and nonalcoholic fatty liver at a time when the obesity epidemic is waning in children.
http://www.vaccines.net/vaccine-induced-immune-overload.pdf
Vaccine-induced immune overload now affects majority of US children, study finds.
Read article here: http://www.thelibertybeacon.com/?p=21474
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A Parent’s Primer: Vasculitis and Vaccines, (more inflammation problems, likely due to the aluminum adjuvants, this time its in the blood vessels)
http://sanevax.org/a-parents-primer-vasculitis-and-vaccines/
How the aluminum adjuvants cause this said inflammation.
J Immunol. 2008 Sep 15;181(6):3755-9. Cutting edge: alum adjuvant stimulates inflammatory dendritic cells through activation of the NALP3 inflammasome.
http://www.ncbi.nlm.nih.gov/pubmed/18768827
Hypothesis Neuro-inflammation, blood-brain barrier, seizures and autism
http://www.jneuroinflammation.com/content/8/1/168
Research The NALP3 inflammasome is involved in neurotoxic prion peptide-induced microglial activation
http://www.jneuroinflammation.com/content/9/1/73/abstract
BRAIN’S IMMUNE SYSTEM TRIGGERED IN AUTISM, (and clueless of them there is of course no mention proposed causation nor vaccines, while sitting right on the smoking gun. Same findings though, without even a thought nor mention of causation )
http://www.hopkinsmedicine.org/Press_releases/2004/11_15a_04.html
Ann Neurol. 2005 Jan;57(1):67-81. Neuroglial activation and neuroinflammation in the brain of patients with autism.
Vargas DL, Nascimbene C, Krishnan C, Zimmerman AW, Pardo CA.
Source: Department of Neurology, Johns Hopkins University School of Medicine, 600 North Wolfe Street, Baltimore, MD 21287, USA.
http://www.neuro.jhmi.edu/neuroimmunopath/pdf/4%20Neuroglial%20activation%20and%20neuroinflammation%20in%20the%20brain%20of%20patients%20with%20autism.pdf
http://www.ncbi.nlm.nih.gov/pubmed/15546155
A couple more examples exist below.
Nanomolar aluminum induces pro-inflammatory and pro-apoptotic gene expression in human brain cells in primary culture
http://www.sciencedirect.com/science/article/pii/S0162013405001182
http://www.ncbi.nlm.nih.gov/pubmed/15961160
Microglial Activation and Increased Microglial Density Observed in the Dorsolateral Prefrontal Cortex in Autism
www.anthro.ucsd.edu/faculty-staff/profiles/files/Morgan_2010.pdf
http://www.sciencedirect.com/science/article/pii/S000632231000497X
http://www.ncbi.nlm.nih.gov/pubmed/20674603
Microglial Activation and Increased Microglial Density Observed in the Dorsolateral Prefrontal Cortex in Autism, (with a list of other related studies)
http://www.journalogy.net/Publication/35542161/microglial-activation-and-increased-microglial-density-observed-in-the-dorsolateral-prefrontal
Immunity, neuroglia and neuroinflammation in autism
http://www.journalogy.net/Publication/6149686/immunity-neuroglia-and-neuroinflammation-in-autism
Blood-brain barrier flux of aluminum, manganese, iron and other metals suspected to contribute to metal-induced neurodegeneration, (and they are injecting newborn infants with hepatitis B vaccine containing an aluminum adjuvant which is recklessly for profit insane)
http://www.ncbi.nlm.nih.gov/pubmed/17119290
Nanomaterials can be transported by monocyte-lineage cells to DLNs, blood and spleen, and, similarly to HIV, may use CCL2-dependent mechanisms to penetrate the brain. This occurs at a very low rate in normal conditions explaining good overall tolerance of alum despite its strong neurotoxic potential. However, continuously escalating doses of this poorly biodegradable adjuvant in the population may become insidiously unsafe, especially in the case of overimmunization or immature/altered blood brain barrier or high constitutive CCL-2 production.
http://www.ncbi.nlm.nih.gov/pubmed/23557144
http://www.biomedcentral.com/1741-7015/11/99
Empirical Data Confirm Autism Symptoms Related to Aluminum and Acetaminophen Exposure
http://people.csail.mit.edu/seneff/Entropy/entropy-14-02227.pdf
How much proof, and as well scientific study proof, would you and should you need? Nothing would be enough, is the attitude of those in the so called medical field and regulatory fields, (and with everything to lose, the truth be known).
The Vaccine Truth-Facts
https://www.youtube.com/watch?v=r0y2t01mqvI
WE DON'T VACCINATE! Myth And Reality Of Vaccination Campaigns (Trailer)
https://www.youtube.com/watch?v=t2cc5J7vlOg&feature=youtu.be
10 Facts Vaccine Companies Don't Want You to Know!
https://www.youtube.com/watch?v=7yqtu9TRi7A
The CDC has to know this. Yet, they're trying to make you believe that if you don't vaccinate your child you're endangering the health of other children. But nothing could be farther from the truth. All the science conducted by independent researchers shows that vaccines can harm your children and grandchildren. This is not some conspiracy theory; it's scientific fact.
http://www.burtongoldberg.com/vaccines.html#.VSBgIDL5Viw.facebook
Dr. Chris Shaw discusses the toxic side effects of Aluminum in Vaccines. Oct-21-2009
